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research Analyse de la régulation du gène Hairless et identification des voies de signalisation affectées chez les mutants «bald Mill Hill».

January 2008 in “HAL (Le Centre pour la Communication Scientifique Directe)”

The mutant HR bmh protein affects hair follicle formation by failing to repress vitamin D receptor activity.

research 1326 Hes1 regulates anagen initiation and hair follicle regeneration through modulation of hedgehog signaling

April 2018 in “Journal of Investigative Dermatology”

research Histopathological and Ultrastructural Study of Ectodermal Dysplasia/Skin Fragility Syndrome

31 citations , August 2005 in “The American Journal of Dermatopathology”

The study concluded that PKP1 is essential for skin integrity and hair growth, and its dysfunction causes the symptoms of ectodermal dysplasia/skin fragility syndrome.

research WIF1 Is Expressed by Stem Cells of the Human Interfollicular Epidermis and Acts to Suppress Keratinocyte Proliferation

18 citations , January 2013 in “Journal of Investigative Dermatology”

WIF1 helps keep skin stem cells inactive to prevent excessive cell growth.

Novel Small Molecules Downregulate CDK1 Expression and Inhibit Wnt/β-Catenin Signaling in Cutaneous Squamous Cell Carcinoma by Targeting Its Distinct Tumor-Specific Cellular Landscape

research Novel small molecules downregulate CDK1 expression and inhibit Wnt/β-catenin signaling in cutaneous squamous cell carcinoma by targeting its distinct tumor-specific cellular landscape

September 2025 in “Experimental & Molecular Medicine”

Small molecules KY19382 and KY19334 may help treat skin cancer by reducing CDK1 levels and blocking harmful cell signals.

research Application of an Enzymatic Method for Identifying Hair Treatments

3 citations , January 2007 in “Journal of health science”

The enzymatic method can effectively identify chemical treatments on hair.

research Abstract 1026: A non-apoptotic function for Mcl-1 as an activator of canonical Wnt signaling in keratinocytes

April 2010 in “Cancer Research”

Mcl-1 can activate Wnt signaling in skin cells, promoting growth and possibly cancer.

research 1434 Epithelially derived MPZL3 negatively regulates murine and human sebaceous gland size and sebocyte proliferation

April 2023 in “Journal of Investigative Dermatology”

MPZL3 protein helps control the size of oil glands and the growth of oil-producing cells in both mice and humans.

research Olorofim Effectively Eradicates Dermatophytes In Vitro and In Vivo

7 citations , September 2021 in “Antimicrobial Agents and Chemotherapy”

Olorofim effectively treats fungal skin infections.

research Marie Unna hereditary hypotrichosis caused by a novel mutation in the human hairless transcript

14 citations , July 2010 in “Experimental Dermatology”

A new mutation in the HR gene causes hair loss in a specific family.

research The transcriptional repressor CDP (Cutl1) is essential for epithelial cell differentiation of the lung and the hair follicle

165 citations , September 2001 in “Genes & development”

CDP is crucial for lung and hair follicle cell development.

research Topical spermine and putrescine stimulated DNA synthesis in the hairless mouse epidermis

10 citations , July 1980 in “British Journal of Dermatology”

Topical putrescine and spermine increased DNA synthesis in hairless mouse skin.

research [An immunohistochemical study on the normal human skin using an anti-hair keratin monoclonal antibody (HKN-2)].

February 1985 in “PubMed”

research Type II Keratins Are Phosphorylated on a Unique Motif during Stress and Mitosis in Tissues and Cultured Cells

80 citations , June 2002 in “Molecular Biology of the Cell”

Type II keratins are uniquely phosphorylated during stress and mitosis, affecting their structure and function.

research Small molecules facilitate single factor-mediated sweat gland cell reprogramming

9 citations , March 2022 in “Military Medical Research”

Small molecules can help turn skin cells into sweat gland-like cells for potential skin repair.

research Ligand‐independent Regulation of the hairless Promoter by Vitamin D Receptor^†

10 citations , February 2008 in “Photochemistry and photobiology”

Vitamin D receptor can control the hairless gene linked to hair loss even without vitamin D.

research Circulating androgen regulation by androgen-catabolizing gut bacteria in male mouse gut

2 citations , July 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”

Certain gut bacteria can lower androgen levels in male mice.

research Two Hypomorphic Alleles of Mouse Ass1 as a New Animal Model of Citrullinemia Type I and Other Hyperammonemic Syndromes

35 citations , August 2010 in “The American journal of pathology”

Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.