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Not having the gene PLAAT3 leads to fat loss, high insulin resistance, and abnormal fat levels in the blood due to a disruption in fat cell development and function.

HR protein causes abnormal hair cycles by increasing Tgf-β2 and reducing miR-31.

Vitamin D receptor is essential for healthy bones and skin.

Mice without Vitamin D receptors have hair growth problems because of issues in the hedgehog signaling pathway.

A single amino acid change in the vitamin D receptor can disrupt its function and lead to hair loss.

Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.

Blocking CYP17A1 enzyme may help improve certain brain function issues related to dopamine.

A genetic mutation in the SGK3 gene causes hairlessness in Scottish Deerhounds and may relate to human hair loss.

PTHrP is important for bone formation and may be targeted for osteoporosis treatment and longevity therapies.

IGFBP5 may be a potential target for Parkinson's treatment by reducing neuron death.

Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.

Hedgehog signaling is crucial for mammary gland development over hair follicles.

Activating Kras in mouse skin causes excess skin and hair loss.

Retinoic acid changes skin cells to mucosal cells with goblet cells, needing TG2/Gh, Gbx1, and TGF-beta.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

Female guinea pigs exposed to less allopregnanolone before birth showed more anxiety-like behavior.

AtVPS29 is essential for proper plant growth by regulating gibberellin signaling.

Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.

Mice with a changed Hr gene lose and regrow hair due to changes in the gene's activity.

FGF5 spliceosomes inhibit rabbit hair growth by affecting gene expression.

Androgen receptor inactivation delays skin cancer onset and reduces incidence in mice, with gender differences in susceptibility.

Alopecia in these mice is caused by defective hair cycle communication due to missing vitamin D receptor function, not vitamin D levels.

Introducing the OTC gene improved symptoms in mice with OTC deficiency.

A mutation in mice causes hair loss and immune problems.

A specific gene region can control targeted and responsive gene expression in mice, useful for skin disorder treatments.

Sex steroids affect the MafB gene differently in male and female hamsters.

DHT deficiency may disrupt rat epididymis function by affecting estrogen receptors.

New mutations in the VDR gene cause vitamin D-resistant rickets without hair loss.

Stopping alcohol after long-term use causes anxiety and changes brain chemicals.

HDAC6 helps keep ovarian follicles dormant, extending female fertility.