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Oxidative Activity of the Type 2 Isozyme of 17β-Hydroxysteroid Dehydrogenase Predominates in Human Sebaceous Glands

research Oxidative Activity of the Type 2 Isozyme of 17β-Hydroxysteroid Dehydrogenase (17β-HSD) Predominates in Human Sebaceous Glands

45 citations , September 1998 in “Journal of Investigative Dermatology”

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

research Characterization of recombinant human liver dehydroepiandrosterone sulfotransferase with minoxidil as the substrate

13 citations , January 1997 in “Biochemical Pharmacology”

Human liver enzyme DHEA ST helps process minoxidil.

research In vitro induction of hair follicle signatures using human dermal papilla cells encapsulated in fibrin microgels

August 2023 in “Cell Proliferation”

Human cells in plasma-derived gels can potentially mimic hair follicle environments, improving hair regeneration therapies.

research 1,314

May 2022 in “Journal of the Dermatology Nurses' Association”

The convention highlighted the importance of comprehensive patient care and early diagnosis in dermatology.

research Excessive hair growth around local β‐interferon injection sites for malignant melanoma

2 citations , December 2015 in “Journal of dermatology”

β-interferon injections for melanoma can cause excessive hair growth at the injection sites.

research Alopecia in vitamin D-dependent rickets type II responding to 1α-hydroxycholecalciferol

3 citations , December 2010 in “Annals of tropical paediatrics”

A boy's hair loss and bone issues improved with specific vitamin D treatment and calcium.

research [Differences in efficacy between drug-eluting beads transbronchial arterial chemoembolization combined with systemic chemotherapy and systemic chemotherapy alone for unresectable lung squamous cell carcinoma].

3 citations , April 2020 in “PubMed”

Combining DEB-BACE with chemotherapy is more effective and has fewer side effects than chemotherapy alone for treating unresectable lung squamous cell carcinoma.

research Overexpression of hypoxia-inducible factor-1α in hidradenitis suppurativa: the link between deviated immunity and metabolism

5 citations , March 2023 in “Archives of dermatological research”

Increased HIF-1α is linked to the inflammation and severity of hidradenitis suppurativa, suggesting treatments that lower HIF-1α could help.

research Identification of compound heterozygous mutations in AP1B1 leading to the newly described recessive keratitis–ichthyosis–deafness (KIDAR) syndrome

11 citations , January 2021 in “British Journal of Dermatology”

Mutations in the AP1B1 gene cause a new syndrome with skin, hearing, and developmental issues.

research The detection of apoptosis and bcl₂ in isolated secondary mohair follicles (growing and quiescent), cultured in vitro in the presence or absence of biotin

1 citations , January 1999 in “Proceedings of the British Society of Animal Science”

Biotin helps maintain hair follicle growth by affecting cell death and survival signals.

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