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April 1995 in “Journal of Medicinal Chemistry” The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.
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April 2009 in “Bioorganic & Medicinal Chemistry Letters” Diphenyl ethers can potentially reduce excess oil production when applied on the skin, helping treat conditions like acne.
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September 1977 in “Journal of Toxicology and Environmental Health” High doses of some contraceptive steroids cause health issues in dogs, but their relevance to humans is unclear.
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June 2018 in “Bioorganic & medicinal chemistry” Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.
October 2024 in “International Journal For Multidisciplinary Research” Wedelolactone may help treat chronic diseases due to its strong antioxidant properties.
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March 2001 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” Key enzymes control androgen levels, affecting hormone activity and potential treatments.
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September 2011 in “American Journal of Clinical Dermatology” Ethinylestradiol/chlormadinone acetate may be an effective and well-tolerated treatment for skin conditions caused by excess androgens.
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July 1974 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Cyproterone acetate combined with ethinyl estradiol significantly reduced hirsutism in women.
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April 1990 in “The Journal of Clinical Endocrinology & Metabolism” The ovary mainly causes high testosterone in PCO, while the adrenal gland is the main source in IH.
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May 1991 in “PubMed” Hirsutism requires identifying the cause to choose the right treatment, which may include medications like oral contraceptives or dexamethasone.
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September 2020 in “Journal of Cosmetic Dermatology” Dexpanthenol improves hair growth and satisfaction in women without side effects.
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August 2000 in “Journal of Pediatric and Adolescent Gynecology” To improve use of the contraceptive DMPA among adolescents, effectively manage side effects like menstrual changes and weight gain through counseling and guidance.
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October 2020 in “Current Drug Discovery Technologies” The research found that compound 6, a newly created steroid, is more effective at inhibiting 5α-reductase (an enzyme) than current treatments, suggesting it could be a better option for treating urinary tract symptoms in men.
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September 1992 in “Steroids” New A-homo-B, 19-dinor steroids showed strong antiandrogenic activity without affecting the enzyme 5α-reductase or androgen receptor binding.
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December 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” Dexamethasone may cause hair loss by stopping cell growth.
January 2022 in “Asian journal of Current Research in Clinical Cancer” Some dibenzo compounds might help treat cancer with fewer side effects.
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October 1988 in “Clinics in Dermatology” Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.
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March 2005 in “Current Medicinal Chemistry” New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.
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June 1989 in “Steroids” Researchers successfully made new compounds for hormone level tests, but one attempt led to an unexpected product, correcting a past error.
Antiandrogens and finasteride may help treat excess hair and hair loss in women.
January 2026 in “Molecules” Dihydroartemisinin could be a versatile cosmetic ingredient but needs more research and development.
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September 2017 in “Journal of Investigative Dermatology” Blocking a specific enzyme can reduce the negative impact of stress hormones on hair growth cells.
September 2024 in “Polish Journal of Public Health” Prescription tablets treat hirsutism, while over-the-counter foams treat hypertrichosis.