research 11β-Hydroxysteroid dehydrogenase type 1 inhibitors for the treatment of type 2 diabetes
Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.
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600-630 / 1000+ results research Discoid lupus erythematosus exacerbated by contact dermatitis caused by use of squaric acid dibutylester for topical immunotherapy in a patient with alopecia areata
Topical squaric acid dibutylester worsened discoid lupus erythematosus in a patient.
research Simultaneous Quantification of Dexpanthenol and Resorcinol from Hair Care Formulation Using Liquid Chromatography: Method Development and Validation
Researchers created a reliable method to measure dexpanthenol and resorcinol in hair products.
research The interaction of hydrocortisone and thyroxine during fetal adipose tissue differentiation: CCAAT enhancing binding protein expression and capillary cytodifferentiation.
Glucocorticoids and thyroid hormones together are essential for fetal fat development.
research [Antiandrogen therapy of acne, falling hair and hirsutism (author's transl)].
Cyproterone acetate is an effective treatment for women with acne, hair loss, and excessive hair growth.
research 557 A peptide derivative with known anti-wrinkle properties was identified as potent dipeptiylpeptidase-4 inhibitor
A peptide known for reducing wrinkles also effectively inhibits an enzyme linked to skin inflammation and acne.
research Detection of cortisol, estradiol, and testosterone in archaeological human hair from the Dakhleh Oasis, Egypt
Ancient hair can preserve hormones, revealing health and fertility insights.
research The serum evaluation of sex hormones including DHEAs, DHT, testosterone in oral lichen planus patients
Sex hormones do not cause oral lichen planus.
research Diabetogenic potential of dexamethasone and effect Annona muricata methanolic bark extract as post-exposure therapy in albino rats
Dexamethasone can cause diabetes in rats, and Annona muricata bark extract may help lower blood sugar.
research Recent advances in thiasteroids chemistry
New sulfur-containing steroid analogs show promise for more targeted medical treatments.
research Synthesis, Crystal Structure and Supramolecular Features of Novel 2,4-Diaminopyrimidine Salts
The salts have diverse molecular packing with significant hydrogen interactions.
research A clinical evaluation of a permanent hair dye designed to reduce allergic contact dermatitis and hair damage
The ammonia-free hair dye is safe and improves hair shine, color, moisture, porosity, and combability.
research Problems in evaluating chronic toxicity of contraceptive steroids in dogs
High doses of some contraceptive steroids cause health issues in dogs, but their relevance to humans is unclear.
research 392 Hair loss after drug reaction with eosinophilia and systemic symptoms: A multicentric retrospective study
Some patients who had a severe drug reaction developed long-term hair loss.
research The effect of spironolactone on genital skin 5α-reductase activity
Spironolactone reduces the enzyme activity that converts testosterone to DHT, helping treat excessive hair growth in women.
research PROGRESSIVE SLEEP APNOEAS RESPOND TO MEDROXYPROGESTERONE ACETATE
Medroxyprogesterone acetate improved sleep apnea symptoms in some obese patients.
research A new method for synthesis of finasteride
A new, safer method to make finasteride from progesterone is effective for industrial use.
research 17 beta-hydroxysteroid dehydrogenase 3 deficiency in the Mediterranean population.
A genetic defect causes males in some Mediterranean populations to be born with ambiguous genitalia and develop male traits at puberty.
research Florid Cushing's Syndrome and Hirsutism Induced by Desoximetasone
Topical corticosteroids can cause serious side effects like Cushing's syndrome and hirsutism.
research Androgenic and anti-androgenic effects of progesterone derivatives with different halogens as substituents at the C-6 position
Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.
research Reduction of Diameter of Hair Shaft among Women with Hirsutism
Spironolactone effectively makes hair shafts thinner in women with excessive hair growth.
research New Synthesis of Methyl 3β-Hydroxy-5-androstene-17β-carboxylate
A new method was developed to make a compound used in finasteride and epristeride with a 69% yield.
research Modern approach to the treatment of patients with androgen-dependent dermatopathies
Cyproterone acetate improves skin symptoms and quality of life in women with androgen-related issues.
research A Soy-Derived Immunostimulating Peptide Inhibits Etoposide-Induced Alopecia in Neonatal Rats
Soymetide-4 from soy can prevent hair loss caused by a cancer drug in rats.
research Effects of 2-Ethylhexanoic Acid on Reproduction and Postnatal Development in Wistar Rats
2-Ethylhexanoic acid harms fertility and delays development in rats.
research Unlocking Dithranol’s Potential: Advanced Drug Delivery Systems for Improved Pharmacokinetics
Advanced delivery systems can make dithranol more effective and less irritating for treating psoriasis.
research Six-year Retrospective Review of Drug Reaction with Eosinophilia and Systemic Symptoms
Early detection and stopping the drug are key to managing DRESS, and careful monitoring is important due to possible severe reactions.
research Recent Progress in Health Benefits of Hederagenin and Its Glycosides
Hederagenin shows promise for cancer and inflammation treatment but needs modifications to improve effectiveness.
research Measurement of level of vitamin D and Antioxidants in Discoid Lupus Erythematosus patients
Patients with Discoid Lupus Erythematosus have lower vitamin D and antioxidant levels and higher oxidative stress.
research Quantification of the Vitamin D Receptor−Coregulator Interaction
Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.