59 citations
,
September 2003 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Epitestosterone may counteract testosterone's effects and has roles in body processes like prostate growth and hair distribution.
20 citations
,
January 2018 in “Expert Opinion on Drug Safety” Personalized treatment with inhibitors, minoxidil, and laser therapy helps hair loss.
18 citations
,
January 1994 in “Skin Pharmacology and Physiology” Androgens shorten hair growth phases, causing finer hair and more severe hair loss in men.
16 citations
,
January 2016 in “Annals of Dermatology” Green tea component EGCG may help prevent hair loss by changing microRNA levels in certain scalp cells.
14 citations
,
April 2006 in “Expert Review of Dermatology” Antiandrogen therapy helps treat genetic hair loss.
14 citations
,
January 1980 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Both treatments reduced androgen levels and hair growth in women with hirsutism.
9 citations
,
October 1991 in “Archives of Dermatological Research” Testosterone, DHT, and estradiol significantly affect hair cell growth.
7 citations
,
January 2004 in “Drugs of today” 5alpha-reductase inhibitors help treat hair loss and prostate issues but may cause sexual side effects.
2 citations
,
November 2017 in “Elsevier eBooks” Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.
2 citations
,
February 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” Androgens like testosterone make Staphylococcus aureus skin infections more common in men.
May 2026 in “Premier journal of science.” Future treatments for hair loss may focus on personalized and regenerative approaches.
August 2025 in “Bioactive Materials” Ac-GFFY-IGF peptide is a promising, safe, and effective treatment for hair loss, better than current options.
June 2025 in “Nanomedicine” Nanotechnology could improve hair loss treatments by delivering drugs more effectively.
March 2024 in “International Journal of Pharmaceutics” Ginsenoside Rg3 combined with minoxidil was more effective in treating hair loss in mice.
March 2021 in “Bioscientia medicina” Androgen affects oil production and hair growth in the skin.
July 2016 in “Journal of Investigative Dermatology” Balding scalps show different gene expressions affecting hair growth compared to non-balding scalps.
Hair loss can be managed with medications, therapies, and lifestyle changes to prevent loss and encourage growth.
December 2024 in “Journal of Population Therapeutics and Clinical Pharmacology” Rosemary and kalonji seeds can improve hair health and treat hair conditions.
Lower DHT and higher testosterone levels increase brain activation but don't change behavior in heavy drinkers.
153 citations
,
April 2009 in “Urology” Prostate cancer was a major health issue in 2009, especially for Black men, and targeting the 5alpha-reductase enzyme could help in its prevention and treatment.
61 citations
,
September 1970 in “Journal of the American Geriatrics Society” Anabolic steroids may help prevent aging effects by reducing toxicity, not by their usual functions.
50 citations
,
July 1996 in “Fertility and Sterility” Finasteride effectively treats hirsutism in women, but more research needed for long-term results.
46 citations
,
October 2012 in “Seminars in reproductive medicine” Genetic defects in androgen production are linked to male developmental disorders and are improving treatment understanding.
34 citations
,
January 2000 in “Journal of Andrology” CAG repeat polymorphism and prostate zone volume are not reliable markers of long-term androgen sensitivity.
31 citations
,
March 2010 in “Molecular Endocrinology” Androgens like testosterone increase colon muscle contractions by affecting calcium pathways.
29 citations
,
November 1975 in “Clinics in endocrinology and metabolism” Testosterone is made by Leydig cells, is active when not bound to proteins, and works by binding to receptors in muscles and other tissues.
24 citations
,
June 2018 in “PubMed” Serenoa repens extract helps regrow hair and repair hair loss by activating certain cell growth pathways.
24 citations
,
January 2010 in “Endocrine Regulations” Taking 1mg of finasteride daily can mildly improve metabolic health and glucose regulation in men with male pattern baldness.
22 citations
,
January 2019 in “Climacteric” Oophorectomy lowers testosterone and estrogen levels in both premenopausal and postmenopausal women, with postmenopausal women still producing significant testosterone.
22 citations
,
May 1986 in “Clinics in endocrinology and metabolism” Certain finger length ratios and body hair patterns may predict side effects from birth control pills in women.