The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.
4 citations
,
January 2016 in “JAMA Dermatology” Compression therapy improved ankle movement, reduced leg swelling, and lessened pain in patients with venous leg ulcers.
79 citations
,
July 2022 in “Sensors” Machine learning can effectively predict type 2 diabetes risk.
July 1998 in “Annals of saudi medicine/Annals of Saudi medicine” A misdiagnosed case of HAIR-AN syndrome led to unnecessary surgeries and highlighted the importance of correct diagnosis and treatment.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Li2CO3 improved skin disease in a mouse model of Focal Dermal Hypoplasia without toxicity.
December 2007 in “Röntgenpraxis” Popliteal Artery Entrapment Syndrome (PAES) is a rare but possible cause of leg pain during walking, even in untrained women.
5 citations
,
March 2016 in “Experimental and molecular pathology” Mice with alopecia areata had wider lymphatic vessels in their skin.
9 citations
,
June 2017 in “The American journal of dermatopathology/American journal of dermatopathology” The study found increased skin pigmentation and variable melanocyte density in a patient with Addison's disease.
68 citations
,
May 2021 in “Endocrine” People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.
People with early-onset hair loss (AGA) have a higher risk of heart disease, metabolic syndrome, and prostate enlargement.
7 citations
,
January 2015 in “Case reports in endocrinology” The document concludes that HAIR-AN syndrome should be considered when a patient shows severe hyperandrogenism and insulin resistance after excluding tumors.
1 citations
,
March 2023 in “International Wound Journal” CCN1 may aid wound healing, but more research with larger samples is needed.
12 citations
,
June 2010 in “Journal of dermatology” Some patients with severe alopecia areata developed skin darkening from their treatment, which may indicate a less effective response to the therapy.
24 citations
,
July 1979 in “Archives of Dermatology” Patients with renal disease may develop vitamin A toxicity even with low-dose supplements.
150 citations
,
October 2012 in “Clinical Endocrinology” Women with PCOS have a higher risk of diabetes and heart problems, especially when they get older.
October 2023 in “Benha Journal of Applied Sciences” Insulin resistance may contribute to hair loss in people with androgenic alopecia.
December 2023 in “PubMed” Metformin and liraglutide improved symptoms of HAIR-AN syndrome in a child.
18 citations
,
April 2013 in “PLOS ONE” Mice with autoimmune hair loss showed signs of heart problems.
1 citations
,
November 2024 in “Blood” PI3Kδ inhibition may effectively treat cutaneous chronic graft-versus-host disease.
June 2025 in “Histopathology” Epithelial elements in superficial angiomyxomas are non-neoplastic growths mimicking embryogenesis.
35 citations
,
January 2006 in “Dermatology Online Journal” Lipedematous scalp may be underdiagnosed and doesn't improve with finasteride.
September 2015 in “Actas Dermo-Sifiliográficas” People with advanced chronic kidney disease often have skin problems, which can be treated with various medications and procedures to improve their quality of life.
June 2021 in “Zenodo (CERN European Organization for Nuclear Research)” Acanthosis nigricans is common in obese individuals, but not significantly linked to obesity type.
January 2025 in “Dermatologic Therapy” Alopecia areata patients don't have increased atherosclerosis risk, but may have higher cardiovascular risk due to smoking, blood sugar, and blood pressure.
1 citations
,
September 2022 in “F1000Research” Digital gangrene can be an initial symptom of late-onset systemic lupus erythematosus.
May 2024 in “Indian Journal of Dermatology” The woman has a rare skin condition called follicular Dowling-Degos disease, which has limited treatment options.
2 citations
,
January 2025 in “Dermatology Practical & Conceptual” Nailfold dermoscopy is a simple, cheap way to check blood vessel changes in COVID-19 patients.
2 citations
,
December 2024 in “Sohag Medical Journal” Insulin resistance can lead to skin problems like acne and psoriasis.
20 citations
,
November 1968 in “The Lancet” Potassium levels affect blood sugar and insulin during dialysis, and malnutrition changes children's hair roots.
April 2024 in “African Journal of Biological Sciences” The patient with lupus and Degos' disease showed significant improvement with treatment.