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Not having the gene PLAAT3 leads to fat loss, high insulin resistance, and abnormal fat levels in the blood due to a disruption in fat cell development and function.

Sebum helps protect human skin from microbes.

Clim proteins are essential for maintaining healthy corneas and hair follicles.

The development of breeding tubercles in male zebrafish relies on a specific enzyme that processes hormones.

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

PAR-1 may play a role in hair growth regulation in human hair follicles.

Mutations in NIPAL4 cause skin issues by disrupting lipid layers, but some improvement is seen with topical treatment.

MFN2 mutations cause mitochondrial problems, unusual fat distribution, and low leptin despite high body fat.

Dlx3 is essential for hair growth and regeneration.

A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

Dermal IgA deposition without symptoms is rare in Dermatitis herpetiformis risk groups.

Hex gene plays a crucial role in starting feather development in chick embryos.

Truncated hHb1 keratin may play a role in breast cancer cell transformation.

The new antibody, TYHF-1, specifically targets certain hair-related structures.

A new gene mutation causes vitamin D resistance and rickets, treatable with calcium therapy.

Mutations in iRhom2 affect hair and skin in mice and are linked to esophageal cancer, with ADAM17 playing a crucial role.

AIRE protein, defective in APECED patients, is found in skin and hair cells and interacts with cytokeratin 17.

Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.

Measuring 24-OHase induction helps identify defects in vitamin D processing and predict treatment response.

Blimp1 is crucial for hair follicle growth and skin health.

Different harmful mutations in the CDH3 gene cause HJMD, but symptoms vary among individuals.

The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.

AP-1 controls tumor cell type by affecting key signaling pathways.

Anti-Desmocollin 3 antibodies can cause pemphigus-like symptoms in mice.

The STRIPAK complex is crucial for skin cell organization and creating a functional skin barrier.

Hairless protein can both repress and activate vitamin D receptor functions, affecting gene regulation.

Knockout mice showed anemia and hair loss, suggesting other ways exist for iron absorption.