research The role of tight junctions in skin barrier function and dermal absorption
Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
Search
for
Sort by
Research
690-720 / 1000+ results 
research Enhancement of follicular delivery of finasteride by liposomes and niosomes
Liposomes and niosomes improve finasteride delivery for hair loss treatment.
research Fullerene nanoparticle in dermatological and cosmetic applications
Fullerenes show potential in skin care but need more safety research.
research Beyond Expectations
Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
research Physiological Regeneration of Skin Appendages and Implications for Regenerative Medicine
The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.
research Targeting lymphoid-derived IL-17 signaling to delay skin aging
Blocking IL-17 signaling may reduce skin inflammation and delay aging.
research 5α-Reductase activity in the human hair follicle concentrates in the dermal papilla
The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.
research Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research Comparative regenerative biology of spiny ( Acomys cahirinus) and laboratory ( Mus musculus) mouse skin
Spiny mice are better at regenerating hair after injury than laboratory mice and could help us understand how to improve human skin repair.
research Priming mobilization of hair follicle stem cells triggers permanent loss of regeneration after alkylating chemotherapy
Chemotherapy causes permanent hair follicle damage by triggering stem cell loss.
research The TFIID subunit TAF4 regulates keratinocyte proliferation and has cell-autonomous and non-cell-autonomous tumour suppressor activity in mouse epidermis
TAF4 is important for skin cell growth and helps prevent skin cancer in mice.
research Hidradenitis Suppurativa
The document concludes that lifestyle changes and medical treatments can significantly reduce symptoms of Hidradenitis Suppurativa, a chronic skin condition.
research Penetration enhancer-containing vesicles (PEVs) as carriers for cutaneous delivery of minoxidil:in vitroevaluation of drug permeation by infrared spectroscopy
PEVs effectively deliver minoxidil through skin.
research Mechanistic Analysis of Human Skin Distribution and Follicular Targeting of Adapalene-Loaded Biodegradable Nanospheres With an Insight Into Hydrogel Matrix Influence, In Vitro Skin Irritation, and In Vivo Tolerability
Researchers developed a nanomedicine for acne treatment that delivers medication with less irritation and is non-irritating for oily skin.
research Niosomes as Carrier in Dermal Drug Delivery
Niosomes are a promising and effective way to deliver drugs through the skin.
research Understanding Microemulsions and Nanoemulsions in (Trans)Dermal Delivery
Microemulsions and nanoemulsions can effectively deliver drugs through the skin, but more research is needed to understand their differences and mechanisms.
research Caffeine and Its Pharmacological Benefits in the Management of Androgenetic Alopecia: A Review
Caffeine improves hair growth, thickness, and reduces shedding.
research The PER3 rs772027021 SNP induces pigmentation phenotypes of dyschromatosis universalis hereditaria
The PER3 rs772027021 SNP may cause mild skin pigmentation changes in a new subtype of dyschromatosis universalis hereditaria.
research Topical SCD-153, a 4-methyl itaconate prodrug, for the treatment of alopecia areata
SCD-153 shows promise as an effective topical treatment for alopecia areata.
research The repression of mètis within digital organizations
Over-reliance on automation limits human problem-solving in emergencies.
research Plakophilin 1 suppresses keratinocyte innate immune responses through DExD/H helicases
Plakophilin 1 helps control skin cell immune responses to prevent excessive inflammation.
research INVESTIGATING THE MECHANISMS UNDERLYING THE PATHOGENESIS OF ALOPECIA AREATA
Alopecia areata may be treated by using EGCG to balance immune cells and reduce inflammation.
research Gender Differences in Production and Circulating Levels of Sex Hormones and Their Impact on Aging Skin
Men and women experience skin aging differently due to changes in sex hormone levels with age.
research Evidence‐Based Medicine in Obstetrics and Gynecology
Accurate diagnosis and timely, tailored treatments improve outcomes in obstetrics and gynecology.
research Physiologic skin changes in pregnancy
Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.
research Progressive Alopecia Reveals Decreasing Stem Cell Activation Probability during Aging of Mice with Epidermal Deletion of DNA Methyltransferase 1
Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.
research The human type I keratin gene family: Characterization of new hair follicle specific members and evaluation of the chromosome 17q21.2 gene domain
The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.
research The Functional Diversity of Epidermal Keratins Revealed by the Partial Rescue of the Keratin 14 Null Phenotype by Keratin 16
K16 can partially replace K14 but causes hair loss and skin issues.
research Developmental genetics of color pattern establishment in cats
Cat color patterns are determined early in development by gene expression and epidermal changes, with the Dickkopf 4 gene playing a crucial role.
research Evidence Suggesting a Role of Iron in a Mouse Model of Nephrogenic Systemic Fibrosis
Iron contributes to skin fibrosis in nephrogenic systemic fibrosis.