88 citations
,
February 2008 in “Journal of Medicinal Chemistry” Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.
15 citations
,
May 2009 in “Steroids” Certain compounds reduced hamster flank organ size by inhibiting 5α-reductase, like finasteride, without affecting androgen receptors.
7 citations
,
June 1989 in “Steroids” Researchers successfully made new compounds for hormone level tests, but one attempt led to an unexpected product, correcting a past error.
June 2010 in “Journal of Chemical Crystallography” The compound was successfully made and shows potential for treating prostate cancer.
66 citations
,
October 1987 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Measuring androstanediol glucuronide in blood is useful for assessing and tracking treatment in women with excessive hair growth.
2 citations
,
December 2008 in “Journal of Chemical Crystallography” The research shows that hydrogen bonds greatly affect the crystal structure of a Finasteride derivative.
February 1999 in “Analytical Sciences” A new antiandrogen compound was made and its detailed three-dimensional shape was described.
September 2020 in “Current Enzyme Inhibition” Three compounds were found to inhibit a prostate disease-related enzyme and reduce prostate size more effectively than the current treatment, suggesting they could be used for treating benign prostatic hyperplasia.
1 citations
,
January 2009 in “X-ray Structure Analysis Online” A new compound was made that might help treat diseases related to male hormones.
59 citations
,
September 2003 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Epitestosterone may counteract testosterone's effects and has roles in body processes like prostate growth and hair distribution.
2 citations
,
January 1975 in “Archives of Dermatological Research” Certain enzymes react strongly with some hormones in rat skin during hair growth, mainly in sebaceous glands and hair sheaths.
20 citations
,
March 2005 in “Current Medicinal Chemistry” New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.
August 2025 in “ACS Omega” New compounds show promise as nonsteroidal treatments for hair loss.
8 citations
,
March 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.
49 citations
,
January 2004 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.
22 citations
,
January 2001 in “Chemical & Pharmaceutical Bulletin” Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.
22 citations
,
January 2017 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” A new method accurately measures nine specific hormones in human blood.
December 2025 in “IP Indian Journal of Clinical and Experimental Dermatology” DNCB is more effective than betamethasone for hair regrowth but has more side effects.
The document's conclusion cannot be provided because the document is not available or cannot be read.
20 citations
,
June 1995 in “Tetrahedron Letters” New chemicals were made that can block an enzyme linked to hair loss, prostate growth, and acne.
193 citations
,
August 1985 in “Endocrinology” Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.
101 citations
,
April 1994 in “Baillière's clinical endocrinology and metabolism” 5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.
58 citations
,
January 2003 in “Biological & Pharmaceutical Bulletin” Bombax ceiba stem bark extracts can lower blood pressure, but high doses can be toxic and lethal.
46 citations
,
September 2011 in “Journal of Endocrinology” Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.
34 citations
,
February 1993 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.
31 citations
,
January 1995 in “The American journal of medicine” Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.
18 citations
,
May 1992 in “American Journal of Biological Anthropology” Higher androgen levels do not cause baldness in men.
17 citations
,
April 1975 in “The Journal of Pediatrics” Minoxidil effectively controls severe high blood pressure in children with few side effects.
12 citations
,
January 1991 in “Archives of dermatological research” Male hormones control a specific gene in hamster skin, with different hormones having varying effects.
3 citations
,
January 2018 Amla oil may help treat hair loss.