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Phytochemicals may offer safer alternatives to synthetic drugs for prostate cancer treatment.

Finasteride reduces AML cell growth by inhibiting androgen receptors.

Different enzymes are active in different parts of developing mouse organs.

A new compound effectively inhibits human 5α-reductase 1.

Inhibiting 5α-reductase during late pregnancy shortens gestation, reduces litter size, and harms memory in rat offspring.

5α-reductase inhibitors are effective for treating hair loss in androgenetic alopecia.

Low-dose finasteride effectively reduces hirsutism without serious side-effects.

Finasteride, when given in high oral doses to pregnant monkeys, caused genital abnormalities in male fetuses, but not in female fetuses or those exposed to intravenous finasteride.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

The body's change of testosterone into DHT is not necessary for testosterone's muscle and sexual effects.

Suppressing certain hormones might help prevent prostate cancer.

Finasteride harms Daphnia magna's reproduction and metabolism.

Finasteride effectively reduces DHT and E2 levels, helping with prostate enlargement.

Stabilizing HIF1A in hair follicles increases glycolysis, which may help reduce oxidative stress and support hair growth.

Finasteride is a safe and effective long-term treatment for prostate enlargement, reducing prostate volume and related symptoms.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.

Tunisian children with hereditary vitamin D-resistant rickets showed improvement with calcium treatment, and new genetic mutations were identified.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

Finasteride reduces hirsutism effectively with fewer side effects but is a second-choice treatment due to safety concerns.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

The new compounds may be more effective and cheaper than current treatments for conditions like baldness.

Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.

SRD5A2 methylation in blood can predict how well someone will respond to finasteride treatment.

Urtica laetevirens extract significantly reduces 5α-reductase activity.

5α-reductase inhibitors help treat prostate enlargement and hair loss but may cause side effects, requiring careful use.

Finasteride blocks progesterone production in specific tumor cells, potentially causing side effects.

Dihydrotestosterone might cause migraines, and finasteride could help reduce them.