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Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Finasteride reduces new brain cells in male mice, possibly causing depression.

A natural steroid in the body may protect against eye damage in glaucoma.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Progesterone and related compounds may help control seizures linked to the menstrual cycle but have limitations that need addressing.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

Finasteride use may lead to less alcohol consumption in men with lasting sexual side effects.

Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.

Finasteride worsens seizures in epilepsy rats and speeds up epileptogenesis in mice.

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.

Finasteride can cause sexual problems and depression in young men.

Consider benefits and risks of new alopecia treatments for safety.

Finasteride blocks progesterone's effect on absence seizures in rats.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Finasteride reduces response to stress and rewards, affecting behavior and mental health.

Dutasteride does not impair mental function in elderly men with enlarged prostate.

Personalized treatment with inhibitors, minoxidil, and laser therapy helps hair loss.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

Finasteride use can cause depression-like behavior in male rats.

Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.

Isoallopregnanolone may be a safe and effective treatment for reducing tics in a mouse model of Tourette syndrome.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.

Certain drugs change freshwater snail shells to a "banana" shape.