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The research gives new understanding on how human steroid 5α-reductases work and how drugs like finasteride inhibit them, which could help in creating new drugs.

Hairless protein and putrescine regulate each other, affecting hair growth and skin balance.

Routine genetic testing is crucial for early diagnosis and better management of Turner’s syndrome with 21-hydroxylase deficiency.

Patients with this syndrome can have different responses and worsening resistance to treatment over time.

Farudodstat can prevent hair follicle immune damage linked to alopecia areata.

CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.

A 7-year-old girl was diagnosed with trichothiodystrophy due to low sulfur levels in her hair.

Two new gene mutations cause a rare hair disorder.

Genetic testing can diagnose hair loss linked to DSG4 gene variants.

Dupilumab effectively treats severe skin issues in a rare genetic disorder.

Thiopurines help treat IBD but require genetic testing to avoid side effects.

Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.

Vitamin D receptor can control the hairless gene linked to hair loss even without vitamin D.

A mutation in the KRTHB5 gene causes hair and nail issues.

A new genetic change in the DSC3 gene is linked to a rare condition causing hair loss and skin blisters in a child.

Targeted protein degraders show promise in treating cancer but need to target more diverse proteins.

Finasteride breaks down into new compounds under acidic conditions.

Hydroxyl radicals cause hair follicle cell death during chemotherapy by reducing Bcl-2 protein levels.

Non-classical 21-hydroxylase deficiency can be missed in newborn screenings and should be considered in cases of early puberty or virilization.

A new compound, HTPI, promotes hair growth by protecting cells from damage and regulating energy use.

Hepatitis C and alcohol abuse may lead to porphyria cutanea tarda.

The GPRC6A-Duox1 axis helps control hair growth and loss by affecting hydrogen peroxide production.

DDR-II hair follicle cells don't respond to 1, 25-dihydroxyvitamin D3, aiding diagnosis.

TTD hair is brittle due to fewer sulfur amino acids and unstable disulfide bonds.

Researchers found a new mutation causing total hair loss from birth.

Two peptides, RMYYY and VMYMI, may be effective anti-inflammatory drugs.

Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.

Equine Cushing's disease in horses causes hormonal imbalance, leading to symptoms like abnormal hair growth and requires lifelong treatment with pergolide.

Nitrendipine and nifedipine effectively block muscle contractions, while papaverine relaxes them and minoxidil needs high amounts to work.

Ca_v1.2 affects hair growth and could be a target for hair loss treatments.