June 2023 in “Clinica Chimica Acta” Finasteride and dutasteride effectively reduce DHT in hair, which may help evaluate their treatment success for hair loss.
February 2023 in “Research Square (Research Square)” Dihydrotestosterone increases arterial stiffness in female mice without changing blood pressure or aortic wall thickness.
January 2023 in “Journal of men's health” Higher dihydrotestosterone may be linked to more inflammation in COVID-19 patients with low testosterone.
October 2022 in “Endocrine journal” Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.
July 2022 in “International Journal of Health Sciences (IJHS) (En línea)” Men with Type 2 Diabetes have lower DHT levels, which may affect fertility and lipid profiles.
June 2022 in “Journal of Experimental Biology and Agricultural Sciences” Higher testosterone harms sperm motility, while higher estradiol improves sperm survival.
April 2022 in “Dermatologic Therapy” Diode laser treatment works better for facial hirsutism in patients with normal hormone levels.
January 2003 in “Humana Press eBooks” Dihydrotestosterone and 5α-Reductase play a role in hair loss and prostate health, and finasteride can increase hair growth in men without affecting sperm production, but it doesn't work for postmenopausal women with hair loss.
Dihydrotestosterone (DHT) and its active metabolites play a key role in various diseases, and the development of 5α-reductase inhibitors can help treat these conditions.
Antiandrogens and finasteride may help treat excess hair and hair loss in women.
March 2023 in “International Journal of Molecular Sciences” ADSC-Exos with miR-122-5p can help treat hair loss by promoting hair growth.
August 2021 in “Asian Journal of Pharmaceutical and Clinical Research” Plant extracts in shampoo improved hair thickness and density in men with hair loss.
January 2009 in “Chinese Journal of Dermatovenereology of Integrated Traditional and Western Medicine” Yifa compound effectively treats female pattern hair loss and lowers DHT and DHEA levels.
58 citations
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January 2006 in “Skin Pharmacology and Physiology” High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.
23 citations
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March 2014 in “International Journal of Molecular Sciences” Testosterone reduces knee flexibility by affecting relaxin receptors.
22 citations
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March 2012 in “Molecular Medicine Reports” DHT affects hair follicle cells by changing microRNA levels, leading to less cell growth and more cell death.
22 citations
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May 1986 in “Clinics in endocrinology and metabolism” Certain finger length ratios and body hair patterns may predict side effects from birth control pills in women.
16 citations
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January 2016 in “Annals of Dermatology” Green tea component EGCG may help prevent hair loss by changing microRNA levels in certain scalp cells.
16 citations
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October 2007 in “Andrologia” DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.
14 citations
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November 1982 in “British Journal of Dermatology” Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.
10 citations
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August 1990 in “Journal of Steroid Biochemistry” High doses of cyclosporine A increase testosterone conversion, possibly boosting hair growth.
8 citations
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July 2017 in “The Journal of Steroid Biochemistry and Molecular Biology” DHT affects testicular development and regulates spermatogenesis in some fish.
8 citations
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August 2015 in “Endocrine”
8 citations
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January 1986 in “Journal of hepatology” Men with liver cancer have higher levels of a specific testosterone byproduct in their liver and blood, despite overall lower male hormone levels.
December 2024 in “Naunyn-Schmiedeberg s Archives of Pharmacology” September 1978 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” 61 citations
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September 1994 in “The Journal of Clinical Endocrinology and Metabolism” 19 citations
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October 1994 in “The Journal of Clinical Endocrinology and Metabolism” 7 citations
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August 1996 in “The Journal of Clinical Endocrinology and Metabolism”
4 citations
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January 2019 in “Annals of Dermatology” RE-ORGA, a Korean herb extract, may help prevent hair loss.