12 citations
,
December 2017 in “Scientific reports” The new test can measure very small amounts of testosterone in hair, and grinding the hair up first gives more accurate results.
November 2024 in “Psychoneuroendocrinology” Testosterone increases hair testosterone levels, stress raises hair cortisol, and relationship status affects hormone levels.
7 citations
,
July 1995 in “PubMed” Finasteride, a drug that changes testosterone to a different hormone, was studied and its effects over time were modeled successfully.
6 citations
,
August 1996 in “The Journal of Clinical Endocrinology and Metabolism” MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.
186 citations
,
December 2011 in “Molecules” Three specific 4-azasteroid-2-oximes showed strong enzyme inhibition, but less than finasteride.
July 2024 in “International Journal of Molecular Sciences” The inhibitor DPP can promote hair growth.
37 citations
,
February 2013 in “Maturitas” Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.
82 citations
,
January 2000 in “Hormone Research in Paediatrics” DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.
Androstenedione is better than testosterone for diagnosing PCOS in Indian women.
12 citations
,
February 2023 in “Applied and Environmental Microbiology” Mutants of CYP154C2 enzyme significantly improved steroid conversion efficiency.
August 2002 in “Analytical Sciences” The document concludes that a compound with potential for treating prostate cancer and hair loss was successfully made and its detailed structure was confirmed.
53 citations
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June 1993 in “Proceedings of the National Academy of Sciences of the United States of America” LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.
8 citations
,
March 2012 in “Mass spectrometry letters” The S9 fraction with GC-IDMS is effective for measuring 5α-reductase activity.
14 citations
,
January 1980 in “Dermatology” Cyproterone acetate temporarily reduces hair growth in women with idiopathic hirsutism but doesn't change hormone levels.
2 citations
,
April 2023 in “Pharmaceuticals” Testosterone therapy for postmenopausal women appears safe and may protect against heart disease, but requires constant monitoring and more research for long-term effects.
18 citations
,
September 1979 in “DMW - Deutsche Medizinische Wochenschrift” Diane is effective for treating acne, seborrhoea, androgenic alopecia, and mild hirsutism in women.
12 citations
,
January 2016 in “Endocrinology, diabetes & metabolism case reports” Testosterone therapy improved physical and social health in a male with 49,XXXXY syndrome.
1 citations
,
January 1979 in “International Journal of Dermatology” Cyproterone acetate effectively treats hirsutism and related conditions.
39 citations
,
August 2004 in “International journal of gynaecology and obstetrics” Finasteride and CPA-EE2 equally reduce hirsutism, but affect hormone levels differently.
June 2025 in “JCEM Case Reports” False high testosterone levels were corrected using a more accurate test.
18 citations
,
January 2002 in “Chemical & pharmaceutical bulletin/Chemical and pharmaceutical bulletin” New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.
February 2010 in “ePrints Soton (University of Southampton)” Male sexual differentiation is regulated independently, while female differentiation occurs in an androgenic environment, affecting conditions like congenital adrenal hyperplasia.
12 citations
,
August 2000 in “Fertility and Sterility” Topical finasteride doesn't reduce DHT levels, hinting at an endocrine role in hair loss.
December 2025 in “IP Indian Journal of Clinical and Experimental Dermatology” Androgenetic alopecia in males is linked to significant psychological distress, highlighting the need for both mental and dermatological care.
98 citations
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July 1983 in “Journal of Steroid Biochemistry” Individuals with this condition often develop male traits and identities at puberty despite being raised as females.
5 citations
,
August 2018 in “Sexual Medicine Reviews” 5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.
7 citations
,
September 2022 in “Communications biology” Omega-6 fats in certain cells boost male hormone production.
8 citations
,
March 2010 in “Gynecological Endocrinology” Free Testosterone Index, bioavailable testosterone, and androstenedione are the most accurate for diagnosing excess male hormones in PCOS.
November 1993 in “PubMed” Hirsutism, excessive male-pattern hair in women, can be caused by high androgens or skin sensitivity, diagnosed by testosterone levels, and treated with hair removal and hormone therapy.
September 1976 in “PubMed” Hirsutism is excessive male-pattern hair growth mainly caused by ovarian hormones, and severe cases may require costly treatment with side effects.