research Drug–Drug Coamorphous System of Tadalafil and Finasteride for Enhanced Pharmaceutical Performance
Combining tadalafil and finasteride improves their solubility and effectiveness.
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research Risk of meningioma among users of high doses of cyproterone acetate as compared with the general population: evidence from a population-based cohort study
High doses of cyproterone acetate are linked to an increased risk of developing meningioma.
research 3,3-Diphenylpentane skeleton as a steroid skeleton substitute: Novel inhibitors of human 5α-reductase 1
A new compound effectively inhibits human 5α-reductase 1.
research Deoxycorticosterone’s anticonvulsant effects in infant rats are blocked by finasteride, but not by indomethacin
Finasteride blocks deoxycorticosterone's anticonvulsant effects in infant rats, but indomethacin doesn't.
research An overview of current strategies and future prospects in drug repurposing in tuberculosis
Drug repurposing offers promising strategies to improve tuberculosis treatment despite challenges.
research THE PEDIATRICIAN AND THE SEXUALLY ACTIVE ADOLESCENT
Pediatricians should advise sexually active teens on safe sex and STD prevention, and discuss contraceptive options and their side effects.
research Dermatitis cruris pustulosa et atrophicans revisited: our experience with 37 patients in south India
DCPA is a chronic leg infection often related to Staphylococcus aureus, affecting mostly young men in India.
research Inhibition of 17α-hydroxylase/C17,20 lyase reduces gating deficits consequent to dopaminergic activation
Blocking CYP17A1 enzyme may help improve certain brain function issues related to dopamine.
research Dihydroartemisinin attenuates benign prostatic hyperplasia in rats by inhibiting prostatic epithelial cell proliferation
Dihydroartemisinin helps reduce prostate enlargement in rats by stopping the growth of prostate cells.
research PNU 157706, a novel dual type I and II5α-reductase inhibitor
PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.
research 2,5-Diazabicyclo[2.2.1]heptane in medicinal chemistry: a treasure trove of therapeutic opportunities
2,5-DBH shows promise for improving drugs in cancer, brain disorders, and infections.
research Experimental Assessment of 3-meta-Pyridine-1,2,4-Oxadiazole Deoxycholic Acid Derivative as a Prototype of 5-α-Reductase Inhibitors in silico and in vivo Models
The new compound is a promising, less toxic alternative to finasteride for treating prostate issues.
research Angle closure in fellow eye with prophylactic pilocarpine treatment
research Molecular insights into the formation of drug-polymer inclusion complex
The research shows how certain drugs can form stable structures with polymers, which is important for making new pharmaceuticals.
research Economic Impact of Home-Use versus Office-Use Diphenylcyclopropenone in Extensive Alopecia Areata
Home-use treatment for severe alopecia areata is as effective as office-use but costs half as much.
research Understanding the formation mechanism of drug-polymer inclusion complex by structure elucidation and theoretical calculation
The research found how certain drugs and polymers form stable complexes, which could help develop new pharmaceutical forms.
research Agitation as a Paradoxical Effect of Divalproex Sodium: A Case Report
Divalproex sodium can unexpectedly cause agitation and hyperactivity in some patients.
research Rational Design and Synthesis of 4-((1R,2R)-2-Hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a Novel, Nonsteroidal Androgen Receptor Antagonist Devoid of Phototoxicity for Dermatological Indications
PF-998425 is a new, effective, and non-phototoxic treatment for skin conditions related to androgens.
research Hair Regrowth Outcomes of Contact Immunotherapy for Patients With Alopecia Areata
Contact immunotherapy can improve hair regrowth in alopecia areata patients.
research Topical photochemotherapy for alopecia areata
Topical PUVA can cause temporary hair regrowth in some alopecia areata patients but doesn't change the long-term outcome.
research VEGF165 modulates proliferation, adhesion, migration and differentiation of cultured human outer root sheath cells from central hair follicle epithelium through VEGFR-2 activation in vitro
VEGF165 influences hair follicle cell growth and movement through VEGFR-2 activation.
research Latanoprost Loaded in Polymeric Nanocapsules for Effective Topical Treatment of Alopecia
research Treatment of Alopecia Areata With Topical Sensitizers
Topical immunotherapy is the best treatment for severe alopecia areata.
research [Selective changes in lymphocytic differentiation antigens in the peripheral blood of patients with alopecia areata treated with oral zinc].
Zinc may help treat alopecia areata by boosting certain immune cells.
research Mesalazine in the treatment of extensive alopecia areata: A new therapeutic option?
Mesalazine may help treat extensive alopecia areata effectively.
research Common Pediatric Skin Conditions with Protracted Courses
Some new treatments for children's skin conditions are effective, but risks must be weighed.
research Evaluation of utility of phenol in alopecia areata
88% phenol is effective for treating alopecia areata.
research Erworbene Alopezien im Kindesalter
Children's hair loss differs from adults, with alopecia areata being most common.
research Therapeutic Approach to Alopecia Areata
research Peripheral neuropathy associated with tofacitinib use in alopecia universalis
A patient developed nerve problems as a side effect of a hair loss treatment called tofacitinib.