86 citations
,
April 2016 in “Nature Communications” Notch1 helps skin heal by attracting specific immune cells.
82 citations
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August 2006 in “Pharmacology, Biochemistry and Behavior” Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.
81 citations
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June 2014 in “Cold Spring Harbor perspectives in medicine” Skin has specialized touch receptors that can tell different sensations apart.
81 citations
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January 2011 in “European Journal of Internal Medicine” Despite progress, better treatments and understanding are needed for the high rates of long-term issues and deaths linked to eating disorders.
80 citations
,
May 2011 in “Nature Cell Biology” New methods have greatly improved our understanding of stem cell behavior and roles in the body.
78 citations
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September 2006 in “International Journal of Cosmetic Science” Dandruff is mainly caused by a scalp reaction to yeast, can worsen hair loss, and antifungal treatments may help.
77 citations
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May 2012 in “Expert Opinion on Emerging Drugs” New treatments for male hypogonadism are effective and should be personalized.
76 citations
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September 1992 in “Endocrinology” The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.
74 citations
,
September 1980 in “Medical Clinics of North America” Toxic epidermal necrolysis is a severe skin condition often caused by drugs, with complex treatment and a high risk of death, but survivors usually heal without scars.
70 citations
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April 2013 in “Endocrine” Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.
69 citations
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September 2006 in “Human Reproduction” Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.
67 citations
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January 2020 in “Cellular & Molecular Immunology/Cellular & molecular immunology” Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.
67 citations
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August 2007 in “American Journal of Pathology” Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.
67 citations
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September 2003 in “Journal of cutaneous pathology” Skin problems are very common in people with end-stage kidney disease.
66 citations
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November 2011 in “Journal of The American Academy of Dermatology” A handheld dermatoscope helps diagnose different types of hair loss effectively.
65 citations
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November 2016 in “Journal of The American Academy of Dermatology” The document concludes that early recognition and treatment of primary cicatricial alopecia is crucial to prevent permanent hair loss.
65 citations
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January 2011 in “Frontiers in Endocrinology” Neurosteroids show promise for treating epilepsy and more research is needed.
65 citations
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August 2007 in “Experimental Dermatology” Human hair follicles can make and process prostaglandins, which may affect hair growth.
64 citations
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January 2004 in “American journal of clinical dermatology” Folliculitis is an inflammation of hair follicles that requires proper diagnosis and treatment based on the specific cause.
64 citations
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January 2002 in “American Journal of Clinical Dermatology” Some patients taking antipsychotic medications experience skin reactions, ranging from mild to severe.
63 citations
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April 2010 in “Development” Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.
63 citations
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January 1984 in “Journal of Investigative Dermatology” Minoxidil promotes hair growth by increasing cell division and DNA synthesis.
62 citations
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March 2008 in “American Journal of Human Genetics” Hair loss gene found on chromosome 3q26.
61 citations
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April 2009 in “British journal of dermatology/British journal of dermatology, Supplement” Docetaxel and paclitaxel for breast cancer can cause permanent, severe hair loss.
61 citations
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October 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” The document concludes that accurate diagnosis is crucial for effectively treating common scalp disorders, which often have similar symptoms.
60 citations
,
September 2015 in “Expert Review of Clinical Immunology” Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.
60 citations
,
April 2006 in “International Journal of Dermatology” Surgical methods like suction blister grafting and split-thickness skin grafting are highly successful for vitiligo repigmentation, but choosing the right patients is crucial for success.
60 citations
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April 2003 in “Human Reproduction” Young Czech women with PCOS have a higher risk of heart problems and should be regularly checked for cholesterol and glucose issues.
59 citations
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August 2007 in “Clinical Endocrinology” The current methods for diagnosing polycystic ovary syndrome are too vague and may lead to misdiagnosis and problems in research.
59 citations
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January 2002 in “Dermatology” A new type of sudden, complete female hair loss was found, with most patients fully recovering within 6 months without needing steroid treatment.