47 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Premature graying of hair may suggest health issues and currently lacks effective treatments.
46 citations
,
August 2019 in “Journal of the European Academy of Dermatology and Venereology” People with hair loss conditions experience more anxiety, depression, and a lower quality of life than those without these conditions.
44 citations
,
November 1998 in “Australasian Journal of Dermatology” Accurate diagnosis is key for treating different kinds of hair loss, and immune response variations may affect the condition and treatment results.
41 citations
,
June 2010 in “Clinics in Dermatology” Smoking harms skin health, causing slower wound healing, more wrinkles, and worsening some skin conditions, but may protect against certain others.
38 citations
,
June 2004 in “Human Reproduction” The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.
36 citations
,
November 2018 in “American Journal of Clinical Dermatology” Alopecia is linked to various health and mental conditions, impacts life quality, and needs medical attention beyond its cosmetic effects.
35 citations
,
February 2023 in “Biomolecules” Granzyme B is important in autoimmune skin diseases and could be a new treatment target.
34 citations
,
March 2015 in “Clinical and Experimental Dermatology” People with pemphigus are more likely to have conditions like hypothyroidism, inflammatory bowel disease, and diabetes.
30 citations
,
April 2017 in “Experimental Dermatology” Hair follicle stem cells and skin cells show promise for hair and skin therapies but need more research for clinical use.
30 citations
,
March 2001 in “Environmental Health Perspectives” Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.
29 citations
,
October 2020 in “eLife” Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.
26 citations
,
October 2020 in “Biomedicines” Bioengineered skin models help reduce animal testing and advance research in cosmetics and skin disease.
26 citations
,
December 2016 in “Pharmacology & Therapeutics” New drugs for heart disease may be developed from molecules secreted by stem cells.
26 citations
,
June 2016 in “Pediatric Dermatology” Premature hair graying in young Turkish adults is more likely if they have stress, a family history of graying, drink alcohol, have chronic diseases, are older, or are taller.
25 citations
,
June 2012 in “Endocrine” PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.
24 citations
,
July 2011 in “PubMed” Thyroid hormones affect skin texture, hair and nail growth, and can cause skin diseases related to thyroid problems.
23 citations
,
November 2020 in “Central-European Journal of Immunology/Central European Journal of Immunology” Alopecia areata, a type of hair loss, is likely an autoimmune disease with a genetic link, but its exact cause is still unknown.
23 citations
,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Alopecia Areata is an autoimmune disease affecting hair follicles, influenced by genetic and environmental factors, with rodent models being essential for research.
21 citations
,
September 2018 in “International journal of women’s dermatology” People with Lichen planopilaris are more likely to have certain autoimmune and endocrine disorders but less likely to have conditions like allergies and diabetes.
21 citations
,
January 2016 in “Skin appendage disorders” Alfredo Rebora suggested a new, easier way to classify hair loss in Telogen Effluvium, adding a type possibly related to autoimmune diseases.
21 citations
,
November 2014 in “Journal of Endocrinological Investigation” Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.
19 citations
,
May 2007 in “Dermatologic therapy” The document concludes that various treatments, including laser therapy, are effective for managing pseudofolliculitis barbae, especially in darker skin types.
18 citations
,
May 2016 in “Annals of Medicine” The article concludes that correctly diagnosing systemic causes of hair loss requires a detailed clinical evaluation and a systematic diagnostic approach.
15 citations
,
August 2021 in “Reviews in endocrine and metabolic disorders” COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.
15 citations
,
October 2016 in “Journal of The European Academy of Dermatology and Venereology” People with hair loss have worse cholesterol levels, possibly linking hair loss to heart problems.
13 citations
,
July 2016 in “Pediatric Dermatology” Loose Anagen Syndrome is more common in females and may be inherited, often confused with other hair disorders, and lacks evidence for biotin treatment effectiveness.
13 citations
,
February 2016 in “Clinical Medicine” The document concludes that diagnosing and treating hair loss is complex and requires understanding its psychological effects and underlying causes, while also calling for more research and new treatments.
12 citations
,
June 2024 in “Archives of Dermatological Research” Older people at home often have skin issues, but there's little evidence on how to prevent or treat them effectively.
12 citations
,
October 2012 in “International Braz J Urol” Finasteride effectively and safely treats recurrent priapism in children and adolescents with sickle cell disease.
12 citations
,
January 2005 in “Journal of Cosmetic Dermatology” AGA affects many, progresses differently, and early treatment is crucial.