research Surgical approach to adolescent obesity
Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.
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research Guidelines of care for androgenetic alopecia
Treat genetic hair loss early with FDA-approved medications and consider hair transplantation.
research Label Retaining Cells (LRCs) with Myoepithelial Characteristic from the Proximal Acinar Region Define Stem Cells in the Sweat Gland
Sweat gland stem cells help maintain glands, aid wound healing, and can regenerate skin structures.
research The bright side of fibroblasts: molecular signature and regenerative cues in major organs
Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.
research Microencapsulated cell tracking
Microencapsulation helps protect and track therapeutic cells, showing promise for treating various diseases, but more work is needed to improve the technology.
research The Clinical Presentation of Systemic Lupus Erythematosus
Systemic Lupus Erythematosus has varied symptoms and is hard to diagnose, affecting many body parts and requiring careful clinical judgment.
research Group IID, IIE, IIF and III secreted phospholipase A2s
Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.
research Defining the identity of mouse embryonic dermal fibroblasts
Researchers identified specific genes that are important for mouse skin cell development and healing.
research <p>Comparison of the Therapeutic Effect of Allogeneic and Xenogeneic Small Extracellular Vesicles in Soft Tissue Repair</p>
Both human and animal-derived small extracellular vesicles speed up skin healing equally well.
research Skin-specific regulation of SREBP processing and lipid biosynthesis by glycerol kinase 5
A gene called Gk5 controls lipid production in the skin and affects hair growth.
research A model system for long-term serum-free suspension organ culture of human fetal tissues: experiments on digits and skin from multiple body regions
Scientists developed a method to grow human fetal skin and digits in a lab for 3-4 weeks, which could help study skin features and understand genetic interactions in tissue formation.
research Recent updates on Wnt signaling modulators: a patent review (2014-2020)
New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.
research The effect of dietary modulation of sulfur amino acids on cystathionine β synthase–deficient mice
Changing the diet of mice lacking the enzyme CBS can affect symptoms related to the genetic condition.
research A review of the sources and pharmacological research of morroniside
Morroniside has many health benefits, including protection against diabetes complications, bone and brain diseases, heart and skin issues, and it supports hair growth and reduces inflammation.
research Alopecia in general medicine
The document concludes that diagnosing and treating hair loss is complex and requires understanding its psychological effects and underlying causes, while also calling for more research and new treatments.
research Quorum sensing and other collective regenerative behavior in organ populations
Organs like hair follicles can renew themselves in complex ways, adapting to different needs and environments.
research Deficiency of the human cysteine protease inhibitor cystatin M/E causes hypotrichosis and dry skin
Lack of cystatin M/E causes thin hair and dry skin.
research Molecular functional analyses revealed essential roles of HSP90 and lamin A/C in growth, migration, and self-aggregation of dermal papilla cells
HSP90 and lamin A/C are crucial for hair growth and could be targets for treating hair loss.
research The correlation between alopecia and temperament in rhesus macaques (Macaca mulatta) at four primate facilities
Monkeys with more anxious or inhibited temperaments tend to have less hair loss.
research Therapeutic potential of endogenous stem cells and cellular factors for scar-free skin regeneration
Using skin stem cells and certain molecules might lead to scar-free skin healing.
research Some Effects Related to the Potassium and Lysine Intake of Rats
Higher potassium intake may protect against hair loss and liver fat in lysine-deficient rats.
research Clinical and genetic findings in a Chinese family with VDR-associated hereditary vitamin D-resistant rickets
A Chinese family had a child with a specific gene mutation causing vitamin D-resistant rickets, but the child improved with calcium and low-dose calcitriol.
research Two mouse mutations mapped to chromosome 11 with differing morphologies but similar progressive inflammatory alopecia
Two mouse mutations cause similar hair loss despite different skin changes.
research Motoneuron-Specific PTEN Deletion in Mice Induces Neuronal Hypertrophy and Also Regeneration after Facial Nerve Injury
Deleting the PTEN gene in mice causes nerve cells to grow larger and heal better after injury, but may cause overgrowth and hair loss in older mice.
research Head and Neck Reconstruction
The document concludes that individualized reconstruction plans are essential for improving function and appearance after head and neck burns.
research Hyperadrenocorticism in Ferrets
Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.
research The role of androgens in hormone replacement therapy
Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.
research Bald thigh syndrome in sighthounds—Revisiting the cause of a well-known disease
Bald thigh syndrome in sighthounds is caused by structural defects in hair shafts due to downregulated genes and proteins.
research Mesenchymal stem cell‐derived exosomes for organ development and cell‐free therapy
MSC-Exos can aid organ development and offer therapeutic benefits for various conditions.
research Immune privilege and alopecia areata
Restoring immune privilege in hair follicles could help treat certain types of hair loss.