research Recent advances in thiasteroids chemistry
New sulfur-containing steroid analogs show promise for more targeted medical treatments.
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510-540 / 1000+ results research Identification of xenobiotics interfering with 5 α -reductase (SRD5A2) activity
MK-0773 is a moderate inhibitor of the SRD5A2 enzyme.
research Characterization of Recombinant Human Liver Thermolabile Phenol Sulfotransferase with Minoxidil as the Substrate
Both enzyme forms can sulfate minoxidil.
research A New Case of Isolated Trichothiodystrophy
A rare case of isolated trichothiodystrophy was identified, marked by brittle hair with low sulfur content.
research Tyrosinase inhibition due to interaction of homocyst(e)ine with copper: the mechanism for reversible hypopigmentation in homocystinuria due to cystathionine beta-synthase deficiency.
Lowering homocyst(e)ine levels can reverse skin and hair lightening by restoring enzyme activity needed for pigmentation.
research Beneficial effects of zinc on reducing severity of depression
Zinc helps reduce the severity of depression.
research Oral zinc sulphate in treatment of patients with thallium poisoning: A clinical therapeutic trial
Oral zinc sulphate is an effective and safe treatment for thallium poisoning.
research Structure optimization of tetrahydropyridoindole-based aldose reductase inhibitors improved their efficacy and selectivity
Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.
research Antipsychotic-Like Properties of 5-α-Reductase Inhibitors
research Effect of the multifunctional cosmetic ingredient sphinganine on hair loss in men and women with diffuse hair reduction
Sphinganine can reduce hair loss and improve scalp health.
research Effect of ethnicity and treatments on in situ tensile response and morphological changes of human hair characterized by atomic force microscopy
Different ethnicities and treatments affect human hair strength and structure.
research Brazilian keratin hair treatment: a review
Brazilian keratin treatments can straighten hair but may contain harmful formaldehyde.
research Convergent Evolution of Cysteine-Rich Keratins in Hard Skin Appendages of Terrestrial Vertebrates
Cysteine-rich keratins evolved independently in mammals, reptiles, and birds for hard skin structures like hair, claws, and feathers.
research Emerging Therapies for Acne Vulgaris
New acne treatments show promise as alternatives to traditional therapies.
research Ten pearls every dermatologist should know about the appropriate use of relaxers
Dermatologists should use hair relaxers carefully to avoid hair and scalp damage, following specific guidelines for application and maintenance.
research Effect of Protein 'Hair Straightener" on Hair Shaft by Scanning Electron Microscopy
Protein hair straighteners damage the hair more than hair dyes.
research Chemically Induced Hair Loss/Alopecia
Some chemicals and drugs can cause hair loss, which usually grows back after stopping the treatment.
research Pharmacological Inhibition of Stearoyl CoA Desaturase in the Skin Induces Atrophy of the Sebaceous Glands
Blocking SCD1 in the skin with XEN103 shrinks sebaceous glands in mice.
research Comparative GC-MS Based In vitro Assays of 5α-Reductase Activity Using Rat Liver S9 Fraction
The S9 fraction with GC-IDMS is effective for measuring 5α-reductase activity.
research Cystathionine β‐synthase‐deficient mice thrive on a low‐methionine diet
Mice with CBS deficiency are healthier on a low-methionine diet.
research A Case of Trichothiodystrophy with a Low Sulfur Level in the Hair Shafts
research Solubilization and Solid‐State Characterization of a Poorly Soluble 5‐α Reductase Inhibitor
GI197111X is best dissolved in Capmul MCM for trials.
research Sulfation of minoxidil by multiple human cytosolic sulfotransferases
Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.
research Crystal structure of Steroid 5-alpha-reductase 2 in complex with Finasteride
research Sulphate conjugation of minoxidil in rat skin
Rat skin can convert minoxidil into its active form, aiding hair growth.
research Serine-rich ultra high sulfur protein gene expression in murine hair and skin during the hair cycle
research Sulfur Containing Tyrosine Analogs Can Cause Selective Melanocytotoxicity Involving Tyrosinase-Mediated Apoptosis
research A Rapid Extraction Procedure of Human Hair Proteins and Identification of Phosphorylated Species.
A new method quickly extracts and identifies proteins from hair and other keratin sources.
research Activin Controls Skin Morphogenesis and Wound Repair Predominantly via Stromal Cells and in a Concentration-Dependent Manner via Keratinocytes
Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.
research Specific receptor detection by a functional keratinocyte growth factor-immunoglobulin chimera.
A new protein was made to detect specific skin cell growth receptors and worked in normal skin but not in skin cancer cells.