36 citations
,
October 2009 in “Journal of biological chemistry/The Journal of biological chemistry” Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.
1 citations
,
January 2018 in “Journal of Gynecologic Surgery” Removing both ovaries can treat increased testosterone and related symptoms in postmenopausal women with ovarian hyperthecosis.
12 citations
,
April 1995 in “Journal of Medicinal Chemistry” The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.
41 citations
,
December 2016 in “International Journal of Women's Dermatology” Hormone therapy and surgeries for transgender individuals affect their skin and hair, requiring specific dermatologic treatments and respectful care.
31 citations
,
January 1989 in “The Prostate/The prostate” Estradiol and castration reduced prostate cancer development in rats when applied at early stages, but were ineffective after cancer was established.
December 2022 in “Urology Herald” Hormonal status from androgen deprivation therapy may affect COVID-19 severity in men.
3 citations
,
February 2021 in “Molecules” A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.
February 2021 in “International Journal of Science and Research (IJSR)” A higher testosterone/dihydrotestosterone ratio in PCOS patients may indicate worse metabolic health.
11 citations
,
May 2022 in “World Journal of Biological Chemistry” Progesterone may help trans women with breast development and health, but more research is needed.
TrichoFoam™ is a stable option for personalized hair loss treatment with most ingredients remaining effective for 90-180 days.
24 citations
,
February 2007 in “Hormone and metabolic research” The substance MK386 effectively blocked testosterone conversion and reduced cell growth in certain skin cells, but inhibiting 5α-reductase alone may not greatly improve acne.
21 citations
,
April 1995 in “Mayo Clinic Proceedings” Leydig cells can cause testosterone-secreting adrenal tumors in women.
April 2020 in “Journal of the Endocrine Society” A rare ovarian tumor that produced testosterone caused a blood clot in the lungs and increased red blood cells in a woman.
18 citations
,
March 2020 in “Frontiers in Neuroendocrinology” The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
186 citations
,
February 2015 in “Frontiers in Neuroscience” Testosterone affects brain behavior in complex and varied ways.
7 citations
,
January 2018 in “Australian Prescriber” Some sports supplements can cause health issues like mood swings, hair loss, and heart problems in men.
56 citations
,
October 1983 in “Archives of Dermatology” Some women with acne have higher levels of free testosterone, which might suggest using hormonal treatments for acne.
January 2005 in “Fuzhou daxue xuebao. Ziran kexue ban” The method is quick and effective for testing steroid 5 alpha-reductase inhibitors.
January 2011 in “Zhongguo xin yao zazhi” A new, safer method to make finasteride from progesterone is effective for industrial use.
August 2014 in “DOAJ (DOAJ: Directory of Open Access Journals)” Testosterone and finasteride showed minor cognitive benefits in older men.
46 citations
,
October 2012 in “Seminars in reproductive medicine” Genetic defects in androgen production are linked to male developmental disorders and are improving treatment understanding.
January 2006 in “프로그램북(구 초록집)”
21 citations
,
January 2010 in “JOURNAL OF HEALTH SCIENCE” Abietic acid from pine resin can effectively inhibit testosterone 5α-reductase.
78 citations
,
March 1989 in “The Journal of Clinical Endocrinology & Metabolism” High-dose androgen therapy can help manage certain types of androgen resistance.
3 citations
,
May 2024 in “Frontiers in Physiology” Sex hormone supplements help improve breathing and nerve recovery after spinal injury in rats.
May 2022 in “Gastroenterology” Supplemental testosterone may lower liver cancer risk in hepatitis C patients.
9 citations
,
January 2017 in “Organic Process Research & Development” In 2017, a new method was created to efficiently produce a topical antiandrogen, a compound used to treat excess sebum and acne, with a high yield and purity.
403 citations
,
November 2005 in “Journal of Endocrinology” Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.
January 1995 in “대한피부과학회지” Higher hormone levels may be linked to female hair loss.
September 2024 in “Journal of the American Academy of Dermatology”