research Stretching the limits: from homeostasis to stem cell plasticity in wound healing and cancer
Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.
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240-270 / 1000+ results research Mitochondria Dysfunction and Inflammation in Traumatic Brain Injury: Androgens to the Battlefront
Androgens like testosterone may help treat traumatic brain injury by reducing mitochondrial stress and inflammation.
research Long-Term Bezafibrate Treatment Improves Skin and Spleen Phenotypes of the mtDNA Mutator Mouse
Bezafibrate treatment improved skin and spleen health in aging mice but didn't extend lifespan.
research Oxidative stress in hair follicle development and hair growth: Signalling pathways, intervening mechanisms and potential of natural antioxidants
Natural antioxidants may help prevent hair loss by reducing oxidative stress.
research Peer Review #1 of "Inflammatory auxo-action in the stem cell division theory of cancer (v0.1)"
The reviewers suggest clarifying and expanding on the role of inflammation in stem cell-related cancer development.
research Premature aging syndromes: From patients to mechanism
Studying premature aging syndromes helps understand human aging and suggests potential treatments.
research Revisiting the role of melatonin in human melanocyte physiology: A skin context perspective
Melatonin affects skin and hair color and protects skin cells, with potential benefits for hair growth and skin health.
research Lgr5+ stem cells and their progeny in mouse epidermis under regimens of exogenous skin carcinogenesis, and their absence in ensuing skin tumors
Lgr5+ stem cells do not cause skin tumors.
research Prevalence of Cobalt in the Environment and Its Role in Biological Processes
Cobalt is important for health but too much or too little can cause health problems, and its environmental buildup is a concern.
research Protein degradation: expanding the toolbox to restrain cancer drug resistance
Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.
research Antioxidant and Antiproliferative Activity of Finasteride against Glioblastoma Cells
High-dose finasteride may help treat glioblastoma but needs localized delivery for effectiveness.
research Targeted disruption of Bcl‐xL in mouse keratinocytes inhibits both UVB‐ and chemically induced skin carcinogenesis
Disrupting Bcl-xL in mice reduces skin cancer risk.
research Highlighting nuances of blue light phototherapy: Mechanisms and safety considerations
Blue light therapy is safe for skin and may protect against UV radiation.
research Generation of the Krt24-CreERT2 Mouse Line Targeting Outer Bulge Hair Follicle Cells
The study created a mouse model to better understand hair follicle stem cells' role in hair growth and repair.
research Administration of Nrf-2-Modified Hair-Follicle MSCs Ameliorates DSS-Induced Ulcerative Colitis in Rats
Nrf-2-modified stem cells from hair follicles significantly improve ulcerative colitis in rats.
research Murine Cytomegalovirus is Not Associated With Alopecia Areata in C3H/HeJ Mice
Murine cytomegalovirus does not cause alopecia areata in these mice.
research Toward Elucidating Epigenetic and Metabolic Regulation of Stem Cell Lineage Plasticity in Skin Aging
Epigenetic and metabolic changes affect stem cell function and aging in skin.
research Involvement of hair follicles in skin tumorigenesis, skin homeostasis and wound healing
Hair follicles are vital for skin health, cancer prevention, and wound healing.
research Anabolic androgenic steroids and carcinogenicity focusing on Leydig cell: a literature review
Anabolic androgenic steroids can increase cancer risk and disrupt hormones.
research Ginseng and ginseng byproducts for skincare and skin health
Ginseng may improve skin health and anti-aging, but how it works is still unclear.
research Overview of Nanocosmetics with Emphasis on those Incorporating Natural Extracts
Nanocosmetics with natural extracts offer benefits but need more research on safety and environmental impact.
research Three-Dimensional-Bioprinted Non-Small Cell Lung Cancer Models in a Mouse Phantom for Radiotherapy Research
3D bioprinted lung cancer models in a mouse-like structure offer a better way to study radiation effects without using live animals.
research Proteomic Analysis of Two Stem Cell Secretomes Used in Combination in a Topical Skin Care Product That Has Demonstrated Efficacy in a Double-Blinded, Vehicle-Controlled Clinical Trial
The combined stem cell secretome in the skin care product effectively reduces inflammation and promotes tissue regeneration.
research Highlights from the Literature
Apoptosis, not oxidative stress, is linked to aging in mice with mtDNA mutations.
research COVID-19 Severity and Androgen Receptor Polymorphism
Men with more CAG repeats in the androgen receptor gene and lower testosterone levels may experience more severe COVID-19.
research Advanced polymer hydrogels that promote diabetic ulcer healing: mechanisms, classifications, and medical applications
Special gels help heal diabetic foot sores and reduce the risk of amputation or death.
research Nano-Enabled CRISPR-Cas Gene Editing for Cancer Therapeutics
Nanotechnology improves CRISPR-Cas9 delivery for cancer treatment, but challenges remain.
research The Multisystem Impact of Long COVID: A Comprehensive Review
Long COVID causes a wide range of long-lasting symptoms that change over time and are hard to diagnose and treat.
research Copper-quercetin complexes: methods of study, relevance to cell death pathways, therapeutic applications
Copper-quercetin complexes could be effective in treating cancer, infections, and promoting bone healing.
research Macrophage activation syndrome in a patient with systemic lupus erythematosus
A patient with lupus experienced a condition where their immune cells became overactive.