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research Stimuli-responsive nanoformulations for CRISPR-Cas9 genome editing

7 citations , August 2022 in “Journal of Nanobiotechnology”

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

research Analysis of Sequences Controlling Tissue-Specific and Hyperproliferation-Related Keratin 6 Gene Expression in Transgenic Mice

26 citations , February 1998 in “DNA and Cell Biology”

K6 gene expression can be controlled and manipulated in mice for studying skin disorders.

research Complete sequence of a hair-like intermediate filament type II keratin gene

15 citations , January 1993 in “DNA sequence”

KRT2.13 gene is similar to KRT2.9 but not expressed in hair follicles.

research A Mutation in the Serum and Glucocorticoid-Inducible Kinase-Like Kinase (Sgkl) Gene is Associated with Defective Hair Growth in Mice

6 citations , January 2004 in “DNA Research”

A mutation in the Sgkl gene causes defective hair growth in mice.

research Isolation and characterization of a sheep cysteine-rich cuticle keratin pseudogene

1 citations , January 1992 in “DNA sequence”

Researchers found a non-functional sheep keratin gene due to mutations.

research Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease

667 citations , May 2008 in “Genes & Development”

Histone demethylases can change gene expression and may be linked to diseases like cancer.

research Histone H3 K4/9/27 Trimethylation Levels Affect Wound Healing and Stem Cell Dynamics in Adult Skin

26 citations , December 2019 in “Stem Cell Reports”

Proper tissue repair in adult skin requires specific histone hypomethylation.

Methylation of CpG Islands in Promoter of Type 2 5-Alpha Reductase and Implications of Finasteride Resistance for BPH Therapy

research 102 Methylation of CpG islands in promoter of type 2 5-α reductase and implications of finasteride resistance for BPH therapy

March 2016 in “European Urology Supplements”

Methylation in specific gene region causes finasteride resistance in some BPH patients.

research Mettl3-catalyzed m ⁶ A regulates histone modifier and modification expression in self-renewing somatic tissue

24 citations , September 2023 in “Science Advances”

Mettl3 is essential for normal tissue development and self-renewal by regulating gene expression.

research Genome-wide Maps of Histone Modifications Unwind In Vivo Chromatin States of the Hair Follicle Lineage

191 citations , September 2011 in “Cell stem cell”

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

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