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research TTNPB Promotes Human Pluripotent Stem Cell‐to‐Neural Stem Cell Transition via Modulation of Chromatin Accessibility and the S‐(5′‐adenosyl)‐L‐homocysteine/Choline Metabolic Network

February 2026 in “Advanced Science”

TTNPB helps turn stem cells into neural stem cells, improving depression-like behaviors in rats.

research The Vitamin D Receptor Is a Wnt Effector that Controls Hair Follicle Differentiation and Specifies Tumor Type in Adult Epidermis

127 citations , January 2008 in “PloS one”

Vitamin D receptor helps control hair growth and could be used to treat certain skin tumors.

research 2‐Deoxy‐d‐glucose enhances tonic inhibition through the neurosteroid‐mediated activation of extrasynaptic GABA_A receptors

44 citations , October 2016 in “Epilepsia”

2-DG reduces seizures by enhancing brain inhibition through specific receptor activation.

research Adverse effects of the 5-alpha-reductase inhibitor finasteride on Daphnia magna: Endocrine system and lipid metabolism disruption

June 2024 in “Ecotoxicology and Environmental Safety”

Finasteride harms Daphnia magna's reproduction, growth, and metabolism.

research Allopregnanolone promotes proliferation and differential gene expression in human glioblastoma cells

25 citations , January 2017 in “Steroids”

Allopregnanolone increases growth and changes gene activity in human brain cancer cells.

research Histone deacetylase inhibitors promote neurosteroid‐mediated cell differentiation and enhance serotonin‐stimulated brain‐derived neurotrophic factor gene expression in rat C6 glioma cells

35 citations , April 2009 in “Journal of Neuroscience Research”

HDAC inhibitors help brain cells grow and improve brain function.

research Repurposing With Purpose: Treatment of Bachmann–Bupp Syndrome With Eflornithine and Implications for Other Polyaminopathies

1 citations , April 2025 in “American Journal of Medical Genetics Part C Seminars in Medical Genetics”

Eflornithine improved symptoms in Bachmann–Bupp Syndrome patients.

5-Bromo-3,4-Dihydroxybenzaldehyde Promotes Hair Growth Through Activation of Wnt/β-Catenin and Autophagy Pathways and Inhibition of TGF-β Pathways in Dermal Papilla Cells

research 5-Bromo-3,4-dihydroxybenzaldehyde Promotes Hair Growth through Activation of Wnt/β-Catenin and Autophagy Pathways and Inhibition of TGF-β Pathways in Dermal Papilla Cells

7 citations , March 2022 in “Molecules”

5-Bromo-3,4-dihydroxybenzaldehyde could potentially help hair growth by activating certain cell pathways and inhibiting others.

research Immunohistochemical expressions of mGluR5, P2Y2 receptor, PLC-?1, and IP3R-I and -II in Merkel cells in rat sinus hair follicles

32 citations , July 2003 in “Histochemistry and Cell Biology”

research The existence of a linear system consisting of sympathetic endings in rat skin

5 citations , August 2005 in “Anatomy and Embryology”

Rat skin has a linear system of nerve fibers linked to hair follicles and muscles.

research Is neuronal inhibition or excitability controlled by Na⁺K⁺2CL^– transporters?

August 2021 in “The Journal of Physiology”

NKCC1 transporters help control neuron excitability and inhibition.

research Corrections to “Adenosine Stimulates Fibroblast Growth Factor-7 Gene Expression Via Adenosine A2b Receptor Signaling in Dermal Papilla Cells”

June 2007 in “Journal of Investigative Dermatology”

research DGAT1 Modulates Hair Cycling and Is Essential for Retinoid Homeostasis in the Skin

June 2007

The enzyme Dgat1 is essential for healthy hair and skin by controlling retinoid levels.

research 1428 DKK2 and SOSTDC1 cooperate to initiate the first catagen phase of the hair follicle growth cycle

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

DKK2 and SOSTDC1 together are necessary for the normal timing of the first regression phase in the hair growth cycle.

research 1406 DETECTION OF MEMBRANE ANDROGEN-BINDING SITE IN LIVING RAT PROSTATE AND EVALUATION OF ITS ROLE IN PROSTATE BLOOD FLOW REGULATION

April 2010 in “The Journal of Urology”

The research found that androgens help control blood flow in the rat prostate through a specific binding site.

research Molecular Interactions of New Pregnenedione Derivatives

20 citations , January 2003 in “Chemical and Pharmaceutical Bulletin”

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

research Proopiomelanocortin expression in the skin during induced hair growth in mice

118 citations , January 1992 in “Experientia”

research Overexpression of the 18 kDa translocator protein (TSPO) in the hippocampal dentate gyrus produced anxiolytic and antidepressant-like behavioural effects

25 citations , June 2017 in “Neuropharmacology”

Increasing TSPO in the brain reduces anxiety and depression.

research Co-operation between follicular ornithine decarboxylase and v-Ha-ras induces spontaneous papillomas and malignant conversion in transgenic skin

88 citations , August 1998 in “Carcinogenesis”

High levels of ODC and a mutant Ha-ras gene cause tumors in mice.

research USO DE ESTIMULAÇÃO CEREBRAL PROFUNDA (DBS) PARA O TRATAMENTO DA DOENÇA DE PARKINSON

October 2022 in “Amplla Editora eBooks”

Deep Brain Stimulation helps manage Parkinson's symptoms when medication isn't enough.

research Extracellular ATP and Adenosine Signaling in Arabidopsis: Investigating Cellular Modulation

May 2025 in “Texas Digital Library (University of Texas)”

Extracellular ATP promotes growth, while adenosine inhibits it in Arabidopsis plants.

research BindingDB Entry 50021519: Discovery of (2S)-N-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-3-(6-(4-cyanophenyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)-2-hydroxy-2-methylpropanamide as a Highly Potent and Selective Topical Androgen Receptor Antagonist for Androgenetic Alopecia Treatment.

January 2025

Oral Administration of Low-Dose Bisphenol A Promotes Proliferation of Ventral Prostate and Upregulates Prostaglandin D2 Synthase Expression in Adult Rats

research Oral administration of low-dose bisphenol A promotes proliferation of ventral prostate and upregulates prostaglandin D₂ synthase expression in adult rats

14 citations , June 2015 in “Toxicology and Industrial Health”

Low doses of BPA can increase prostate growth and change hormone levels in adult rats.

research Telogen effluvium as a clinical presentation of human immunodeficiency virus infection

5 citations , April 2002 in “The American Journal of Medicine”

Hair loss can be an early sign of HIV infection.

research Androgen binding profiles of two distinct nuclear androgen receptors in Atlantic croaker (Micropogonias undulatus)

58 citations , June 2000 in “The Journal of Steroid Biochemistry and Molecular Biology”

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

research Discovery of a transdermally deliverable pentapeptide for activating AdipoR1 to promote hair growth

8 citations , September 2021 in “EMBO Molecular Medicine”

A new small peptide may help hair growth by activating a specific receptor and should be tested in humans.

research Dihydroartemisinin attenuates benign prostatic hyperplasia in rats by inhibiting prostatic epithelial cell proliferation

4 citations , August 2021 in “Annals of Translational Medicine”

Dihydroartemisinin helps reduce prostate enlargement in rats by stopping the growth of prostate cells.

research Discovery and Clinical Development of Dutasteride, a Potent Dual 5α- Reductase Inhibitor

58 citations , March 2006 in “Current topics in medicinal chemistry”

Dutasteride effectively treats benign prostatic hyperplasia and may reduce prostate cancer risk.

research DHEA and frontal fibrosing alopecia: molecular and physiopathological mechanisms

31 citations , December 2016 in “Anais Brasileiros de Dermatologia”

DHEA reduction may be linked to frontal fibrosing alopecia, but more research is needed.

research Heterozygous Arrhythmogenic Cardiomyopathy-desmoplakin Mutation Carriers Exhibit a Subclinical Cutaneous Phenotype with Cell Membrane Disruption and Lack of Intercellular Adhesion

4 citations , October 2021 in “Journal of Clinical Medicine”

Carriers of a specific gene mutation have subtle skin changes without visible symptoms.

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