510 citations
,
August 2006 in “Endocrinology” The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.
25 citations
,
July 2006 in “Journal of Neurochemistry” Progesterone affects GABAA receptor function by altering δ subunit levels.
The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.
14 citations
,
April 2005 in “Experimental Dermatology” Stressed fibroblasts greatly increase melanin production in hair, skin, and eye cells, mainly due to a growth factor called bFGF.
5 citations
,
March 2016 in “Acute medicine & surgery” Swallowing a lot of minoxidil, a hair growth liquid, can cause severe and long-lasting low blood pressure.
3 citations
,
March 2019 in “Post Reproductive Health” Testosterone replacement can help menopausal women with various symptoms, but should be used carefully and is not yet officially licensed in the UK for women.
98 citations
,
July 2006 in “Neuropsychopharmacology” June 2026 in “The Journal of Steroid Biochemistry and Molecular Biology”
December 2022 in “Acta Ophthalmologica” Dutasteride potentially improves cell survival and reduces retinal damage in retinitis pigmentosa.
2 citations
,
February 2019 in “Journal of Investigative Dermatology” Higher levels of the DP2 receptor may lead to hair loss.
62 citations
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January 2009 in “Biochemistry” Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.
44 citations
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January 1999 in “Advances in pharmacology” The document concludes that the androgen receptor's structure and function are complex, affecting how it regulates genes and is involved in diseases like prostate cancer.
2 citations
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July 2021 in “UNC Libraries” Mutations at Val-889 and Arg-752 disrupt key interactions in androgen receptor dimerization.
October 2023 in “IBRO neuroscience reports” Rat hair follicle stem cells have functional oxytocin receptors, useful for studying neuropsychiatric disorders.
227 citations
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January 1998 in “Journal of biological chemistry/The Journal of biological chemistry” Mutations at Val-889 and Arg-752 disrupt key interactions in the androgen receptor, affecting its function.
15 citations
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June 2019 in “Biochemical Journal” A new genetic disorder caused by an ODC1 mutation can be treated with DFMO.
59 citations
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February 1998 in “Chemico-Biological Interactions” Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.
18 citations
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November 1994 in “Histochemical Journal” The enzyme PST is found in developing human kidneys and helps with detoxification and development.
11 citations
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February 2013 in “Clinical Endocrinology” A small number of premenopausal female blood donors had high prolactin levels, often due to stress, and retesting is recommended to prevent misdiagnosis.
10 citations
,
June 2006 in “Fertility and Sterility” The conclusion is that metformin is a first-line treatment for PCOS, particularly for restoring ovulation and increasing pregnancy rates, with other treatments depending on specific symptoms.
6 citations
,
August 2005 in “The Journal of Clinical Endocrinology & Metabolism” Finasteride causes temporary cell death in BPH tissues.
4 citations
,
May 2020 in “Medicine in Drug Discovery” The study developed a method to detect minoxidil and its sulfate form, found that minoxidil sulfate is temperature-sensitive, and identified a way to potentially increase its stability for hair loss treatment.
1 citations
,
August 2023 in “arXiv (Cornell University)” Deep learning effectively diagnoses scalp disorders, but improvements are needed.
New hydrogel sensors can be quickly made and customized for wearable devices.
November 2023 in “Regenerative Biomaterials” The new adhesive seals wounds quickly, works well in wet conditions, and helps with healing.
June 1995 in “International Journal of Gynecology & Obstetrics” Long-term use of oral contraceptives, especially starting before age 20, may increase the risk of early-onset breast cancer.
June 1995 in “International Journal of Gynecology & Obstetrics” Higher doses of oestradiol implants improve bone density in postmenopausal women.
June 1995 in “International Journal of Gynecology & Obstetrics” Cabergoline is more effective and has fewer side effects than bromocriptine for treating women with hyperprolactinemic amenorrhea.
39 citations
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November 2007 in “Experimental dermatology” Human hair follicles contain a complex network of prostanoid receptors that may influence hair growth.
4 citations
,
May 2022 in “Genes & Diseases”