research High spatial resolution study of human skin using synchrotron infrared microscopy: application to the penetration of external agents
External agents penetrate skin more easily in areas with fewer lipids, especially through hair follicles.
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research Transferosomes: Unique vesicular carriers for effective transdermal delivery
Transferosomes effectively deliver drugs through the skin, improving treatment for skin disorders.
research Immunohistochemical localization of fatty acid transporters and MCT1 in the sebaceous glands of mouse skin
Sebaceous glands help study fatty acid transporters and binding proteins.
research Spatial transcriptomics reveals asymmetric cellular responses to injury in the regenerating spiny mouse (Acomys) ear
The spiny mouse regenerates ear tissue asymmetrically, with gene expression differences possibly explaining its unique healing abilities.
research Recent advances in drug repositioning and rediscovery for different therapeutic activities utilizing updated technological approaches
Using existing drugs for new treatments is cost-effective and safer.
research [Transplanted epidermal neural crest stem cell in a peripheral nerve gap].
Epidermal neural crest stem cells from hair follicles can help repair nerve injuries.
research 551 Combining Laser Capture Microdissection and RNAseq Analysis to Generate a Human Anagen Hair Follicle Transcriptome Atlas
Researchers made a detailed map of gene activity for different parts of human hair follicles to help create targeted hair disorder treatments.
research Las sucesiones mortis causa transfronterizas en la Unión Europea
A combined strip and FUE method with careful planning improves hair restoration results.
research 779 Multicellular skin organoids as a unique modeling platform for skin physiology, injury, and disease
The new skin organoid system effectively mimics human skin for studying its functions, injuries, and diseases.
research Optimal Hair Transplant Recipient Site Slit Design: Minimizing Vascular Damage
Semiconical blades and coronal slits minimize vascular damage in hair transplants.
research Alopecia induced by dopamine agonists
Dopamine agonists like pramipexole and ropinirole can cause reversible hair loss.
research Molecular insights into chronotype and time-of-day effects on decision-making
People's decision-making can be influenced by their internal biological clocks, as shown by gene expression, not just self-reported preferences for morning or evening.
research Skin-resident immune cells actively coordinate their distribution with epidermal cells during homeostasis
Skin cells control immune cell placement, helping the skin respond better to challenges.
research Effect of physical stimuli on hair follicle deposition of clobetasol-loaded Lipid Nanocarriers
NLCs with manual massage greatly improve clobetasol delivery to hair follicles.
research 1389 Local injection with anti-herpes simplex virus antibodies protects against development of herpes simplex virus–induced sweating disturbance
Injecting anti-herpes antibodies locally can prevent skin lesions and sweating problems caused by herpes simplex virus in mice.
research Dual‐flow‐RootChip reveals local adaptations of roots towards environmental asymmetry at the physiological and genetic levels
Roots adapt to uneven environments by changing growth and gene expression.
research Functional redundancy of Frizzled 3 and Frizzled 6 in planar cell polarity control of mouse hair follicles
Frizzled 3 and Frizzled 6 together control the orientation of mouse hair follicles.
research 5alpha-reductase inhibitors dampen L-DOPA-induced dyskinesia via normalization of dopamine D1-receptor signaling pathway and D1-D3 receptor interaction
Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.
research Biosynthesis of Dihydrotestosterone by a Pathway that Does Not Require Testosterone as an Intermediate in the SZ95 Sebaceous Gland Cell Line
Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.
research Surgical Assistants Corner: Design elements in zone planning for hair transplantation: part I
Designing the hair transplant area is important for a successful surgery.
research To σύνδρομο της δερματίτιδας από λείξη των άκρων στο σκύλο
Canine acral lick dermatitis is a complex skin issue in dogs caused by excessive licking, often needing various treatments.
research Mnemonics in dermatology; an appraisal
Mnemonics help remember dermatology information.
research The Organizer and Beyond
Cells from certain embryo parts can induce head formation in another embryo, involving complex signaling pathways.
research TRP Channels in Skin Biology and Pathophysiology
TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
research Decision letter: Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis
Neutrophils are key in causing chronic itch in atopic dermatitis, and blocking CXCR3 could reduce this itch.
research Androgen‐induced neurite outgrowth is mediated by neuritin in motor neurones
Androgens help motor neurons grow by increasing neuritin.
research Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism
Blocking the ATX-LPA pathway may improve insulin sensitivity and mitochondrial function in obesity.
research Mandibulofacial dysostosis with alopecia results from ETAR gain-of-function mutations via allosteric effects on ligand binding
Specific mutations in a receptor cause facial abnormalities and hair loss.
research 50570 Irritation and sensitization potential of approved topical and transdermal delivery systems – A retrospective study
Generic topical and transdermal systems usually cause minimal irritation or sensitization.
research ESDR382 - Environmental pathobiology of frontal fibrosing alopecia (FFA): Does linalool promote FFA development and progression by inducing epithelial hair follicle stem cell damage and MICA expression in the bulge?
Linalool in personal care products may worsen frontal fibrosing alopecia by damaging hair follicle stem cells and triggering harmful immune responses.