122 citations
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December 2022 in “International Journal of Molecular Sciences” Nanoparticles improve skin treatment but need more research on safety and effectiveness.
119 citations
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November 2016 in “American journal of human genetics” Mutations in three genes cause Uncombable Hair Syndrome, leading to frizzy hair that can't be combed flat.
91 citations
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June 2011 in “The EMBO Journal” TCF/Lef1 activity is essential for proper skin cell development and renewal.
86 citations
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April 2009 in “Journal of anatomy” Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.
79 citations
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August 1998 in “The Journal of Cell Biology” Keratin 16 delays skin maturation and affects skin and hair development in mice.
71 citations
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June 2005 in “Journal of Investigative Dermatology” PAD enzymes play a key role in hair growth and structure.
45 citations
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August 2018 in “Stem Cells International” Stem cells, especially from fat tissue and Wharton's jelly, can potentially regenerate hair follicles and treat hair loss, but more research is needed to perfect the treatment.
43 citations
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October 2006 in “Journal of Cell Science” Keratin 10 end domains may increase skin cancer risk by reducing cell death.
40 citations
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January 2018 in “International journal of trichology” Healthy scalp reduces hair loss by managing oxidative stress.
35 citations
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January 2020 in “Skin Pharmacology and Physiology” The review concluded that keeping the hair-growing ability of human dermal papilla cells is key for hair development and growth.
35 citations
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June 2012 in “PloS one” Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.
31 citations
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August 2015 in “Stem Cells Translational Medicine” Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.
26 citations
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September 2023 in “Bioengineered” Brown seaweed oligosaccharides have health benefits and potential uses in food and medicine.
26 citations
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June 2016 in “Frontiers in Plant Science” Autofluorescence can sort plant cells without labeling.
20 citations
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August 2022 in “Frontiers in Immunology” Fibroblasts are important in healing diabetic wounds, but high sugar levels can harm their function and slow down the healing process.
20 citations
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November 2021 in “Frontiers in cell and developmental biology” Skin organoids from stem cells could better mimic real skin but face challenges.
17 citations
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September 2016 in “Stem cells translational medicine” Using bioreactors, scientists can grow more skin stem cells that keep their ability to regenerate skin and hair.
16 citations
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April 2021 in “Frontiers in Cell and Developmental Biology” New hair follicles could be created to treat hair loss.
15 citations
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January 2023 in “Biomaterials Research” 3D bioprinting in plastic surgery could lead to personalized grafts and fewer complications.
15 citations
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January 2020 in “ILAR Journal” Nonhuman primates are valuable in research but their natural health variations can complicate study results.
14 citations
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September 2024 in “Cosmetics” Exosomes and cell culture-conditioned media improve skin quality and reduce aging signs.
11 citations
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October 2021 in “Frontiers in Cell and Developmental Biology” Non-coding RNAs are important for hair growth and could lead to new hair loss treatments, but more research is needed.
9 citations
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May 2025 in “Stem Cell Research & Therapy” Extracellular vesicles can both worsen and help treat age-related diseases and are useful for early diagnosis.
9 citations
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October 2024 in “Burns & Trauma” Air-liquid interface culture improves hair follicle development in skin organoids.
9 citations
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September 2022 in “Journal of Clinical Investigation” Replacing defective mesenchymal cells with normal ones fixes thymic growth issues in 22q11.2DS mouse models.
7 citations
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January 2023 in “Journal of Hematology & Oncology” Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.
7 citations
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March 2017 in “Experimental and Therapeutic Medicine” Hair follicle cells can help keep embryonic stem cells undifferentiated.
6 citations
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November 2022 in “Development” New research shows that skin diversity is influenced by different types of dermal fibroblasts and their development, especially involving the Wnt/β-catenin pathway.
5 citations
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November 2024 in “Advanced Science” A new culture system can grow tooth-like structures from dental cells but can't yet develop roots.
3 citations
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May 2024 in “Biomimetics” Bioactive biopolymers can improve diabetic wound healing by enhancing tissue regeneration.