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A new method accurately measures DHEAS in blood, improving on current tests.

Enriching the French health care database with external data greatly improved its usefulness.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

A specific gene variant is linked to heart disease, increased heart muscle, curly hair, and thick skin on palms and soles.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

5-alpha-reductase inhibitors might help slow down low-risk prostate cancer, but their use should be cautious.

5-alpha-reductase inhibitors help treat urinary symptoms from an enlarged prostate.

Patients on psoriatic drugs need regular dental check-ups to prevent oral issues.

Anti-DFS70 antibodies can help identify nonsystemic autoimmune conditions in SLE patients.

VDDR I and II are genetic disorders affecting vitamin D use, causing rickets, with VDDR I treatable by vitamin D supplements and VDDR II needing high doses and calcium.

In STSD patients, the body compensates for low androgen levels by increasing another enzyme's activity.

The research gives new understanding on how human steroid 5α-reductases work and how drugs like finasteride inhibit them, which could help in creating new drugs.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Computational techniques can improve drug development for treating certain conditions.

Men taking dutasteride may have a higher risk of age-related macular degeneration.

The index to ring finger ratio may indicate disease severity in female ankylosing spondylitis patients, but not in males.

Clinicians should use social and prescription data to track trends in performance-enhancing drug use.

Dutasteride is linked to a higher chance of sexual dysfunction, especially in younger males and the elderly.

5α-reductase affects dopamine receptors linked to sensorimotor gating, which may help understand disorders like schizophrenia.

Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.

SARM-induced changes in the androgen receptor are specific to each ligand and affect stability and protein interactions.

Patients with the same genetic mutation for vitamin D-resistant rickets showed different symptoms but all improved with treatment except for hair loss.

Stereotactic body radiation therapy and radiosurgery are advanced, precise treatments that target tumors while protecting healthy tissue.

The treatment was not recommended due to limited effectiveness and significant side effects.

Certain medications, especially 5-alpha reductase inhibitors, are commonly linked to erectile dysfunction.

Sry may regulate fatty acid metabolism and shows different expression levels in rat tissues.

Human liver enzyme DHEA ST helps process minoxidil.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

DS-2325a is safe and well-tolerated, supporting further development for Netherton Syndrome treatment.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.