research Identification of drug-specific public TCR driving severe cutaneous adverse reactions
Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.
Search
for
Sort by
Research
390-420 / 1000+ results 
research Transfollicular Drug Delivery: Penetration of Drugs Through Human Scalp Skin and Comparison of Penetration Between Scalp and Abdominal Skins In Vitro
Drugs penetrate scalp skin better than abdominal skin, with scalp hair follicles aiding in higher drug delivery.
research Gender Differences in Skin Aging and the Changing Profile of the Sex Hormones with Age
The document concludes that there are still unknowns about the effectiveness, risks, and detection of performance-enhancing drugs, and doping remains a challenge.
research Hyperbranched glycerol-based core-amphiphilic branched shell nanotransporters for dermal drug delivery
New nanocarriers improve skin drug delivery with low toxicity at certain concentrations.
research Establishment of an evaluation method to detect drug distribution in hair follicles
Researchers developed a method to measure drugs in hair follicles and found that both water-loving and fat-loving drugs can be detected after being applied to the skin.
research Chemotherapy and Cutaneous Drug Reactions
Chemotherapy can cause skin side effects that affect patients' lives, but they can be managed to avoid interrupting cancer treatment.
research Enhancement of drug permeation across skin through stratum corneum ablation
Removing the outer skin layer increases drug absorption and offers non-invasive treatment options, with some methods allowing for quick skin recovery.
research A Simple Decision Tree Suited for Identification of Early Oral Drug Candidates With Likely Pharmacokinetic Nonlinearity by Intestinal CYP3A Saturation
The decision tree can predict drug absorption issues with good accuracy but needs more validation and adjustments for other factors.
research Extracellular vesicle-based drug overview: research landscape, quality control and nonclinical evaluation strategies
Extracellular vesicles show promise for treating diseases but face challenges in development and regulation.
research FGF Family: From Drug Development to Clinical Application
FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.
research Ayurveda & Bioactives as Adjuvant for Dna Modulation in Cancer Treatment & Adverse Drug Reaction [ADR] – A Glimpse of Traditional Indian Nanotechnology
Ayurvedic herbs may reduce side effects and improve effectiveness of cancer treatments.
research Advancements in transdermal drug delivery using microneedles: technological and material perspective
Microneedle patches offer painless, effective drug delivery and are suitable for all ages.
research NANOEMULGEL AS A RECENT DRUG DELIVERY SYSTEM
Nanoemulgel is a promising method for delivering drugs, especially for those that don't dissolve well in water.
research Nanoformulation of Medicinal Plant Compounds for Improved Drug Delivery and Pharmacological Activity
Nanotechnology improves the effectiveness of medicinal plant compounds in drug delivery.
research Progress in the design of ascorbic acid derivative-mediated drug delivery
Ascorbic acid derivatives improve drug delivery systems.
research Large Scale Gene Expression Profiles of Regenerating Inner Ear Sensory Epithelia
Birds can regenerate inner ear cells using specific gene pathways, unlike mammals.
research Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells
Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.
research Investigation of drug partition property in artificial sebum
The conclusion is that measuring how drugs partition into artificial sebum is important for predicting their delivery into hair and sebaceous follicles, and it provides better information than traditional methods.
research Neonatal finasteride induces anxiogenic-like profile and deteriorates passive avoidance in adulthood after intrahippocampal neurosteroid administration
Finasteride given to baby rats causes anxiety-like behavior and worsens learning from punishment in adult rats.
research Leucaena Leucocephala a Nutrition Profile
Leucaena leucocephala is nutritious but needs careful processing to remove toxins.
research Spontaneous cutaneous adverse drug reaction reports—An analysis of a 10‐year dataset in Singapore
In Singapore, most skin reactions to drugs were in females and Chinese, often caused by painkillers, antibiotics, and some other drugs, with serious cases linked to genetics.
research Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases
New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
research Metformin: Old Drug, New Therapeutic Potential in the Skin? A Brief Narrative Review
Metformin may help treat various skin conditions and aid in wound healing and skin aging.
research A microscopy-based small molecule screen in primary neurons reveals neuroprotective properties of the FDA-approved anti-viral drug Elvitegravir
The anti-viral drug Elvitegravir may protect brain cells from damage related to neurodegenerative diseases.
research An Overview on Ethanopharmacological Profile of Bacopa Monniera
Bacopa monniera promotes hair growth, enhances memory, and helps with inflammation and stomach issues.
research Impact of Chemotherapeutic Drug on People living with Cancer
Fasting may reduce chemotherapy side effects.
research EX VIVO DRUG SENSITIVITY EVALUATION OF A RARE ZMYM2::FGFR1+ LEUKEMIA PATIENT
Pemigatinib may be effective for treating ZMYM2::FGFR1 fusion-positive leukemia.
research Cutaneous Adverse Drug Reactions to Antibiotics: How Much is the Extent of the Problem?
Antibiotics often cause skin reactions, making them a major health concern.
research Grand challenges in dermatologic drug discovery: four priorities to transform skin disease treatment
Transforming skin disease treatment requires new strategies, better drug models, and patient-focused research.
research The role of aquaporins in polycystic ovary syndrome – A way towards a novel drug target in PCOS
Aquaporins could be new drug targets for treating polycystic ovary syndrome.