The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.
January 2005 in “mediaTUM – the media and publications repository of the Technical University Munich (Technical University Munich)” Vitamin D and glucocorticoids affect bone growth, metabolism, and immune response.
54 citations
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April 2010 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.
September 2022 in “Annals of medicine and surgery” Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.
April 2025 in “Antioxidants” Rhus semialata gall extract and Penta-O-Galloyl-β-D-Glucose may effectively reduce hair loss.
July 2021 in “Advances in laboratory medicine” Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.
6 citations
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March 2022 in “Molecules” Methyl jasmonate boosts tanshinone production in Salvia miltiorrhiza callus cultures.
2 citations
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January 1989 Tay syndrome is a unique genetic disorder causing skin, hair, and developmental issues.
January 2026 in “Academic Journal of International University of Erbil” Rural residents have higher vitamin D levels than urban residents in Erbil.
May 2025 in “Süleyman Demirel Üniversitesi Fen Edebiyat Fakültesi Fen Dergisi” Minoxidil is compatible with some excipients but not with others, affecting formulation choices.
4 citations
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November 2022 in “Nutrients” Cow placenta extract has strong antioxidant effects and can delay skin aging in mice.
6 citations
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February 2022 in “JAAD International” Higher doses of isotretinoin may lead to more hair loss.
417 citations
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March 1991 in “American Journal of Psychiatry” Most adult chronic hair pullers are women who started in their early teens, often have other mental health issues, and may pull hair due to underlying psychiatric conditions.
208 citations
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December 2003 in “Journal of Investigative Dermatology” Certain cells from hair follicles can create new hair and contribute to hair growth when implanted in mice.
131 citations
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July 2009 in “Experimental Dermatology” The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.
108 citations
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July 2002 in “Molecular and cellular biology” Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.
96 citations
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September 1996 in “PubMed” Desmocollin 1 and 3 have distinct patterns in human tissues, with Dsc1 in specific skin and hair layers and Dsc3 in various epithelial layers.
81 citations
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March 2006 in “Journal of Investigative Dermatology” Mutations in the DSG4 gene cause specific hair and scalp issues.
74 citations
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January 2006 in “The journal of investigative dermatology/Journal of investigative dermatology” Mutations in the DSG4 gene can cause a rare hair disorder similar to monilethrix.
63 citations
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November 2015 in “Pharmaceutical Sciences” Nanophytosomes can improve the delivery and effectiveness of herbal medicines like Rutin.
52 citations
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May 2015 in “Cytotherapy” DS-MSCs from hair follicles may improve diabetic wound healing.
50 citations
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February 2004 in “Genomics” A gene mutation causes lanceolate hair in rats by disrupting hair shaft integrity.
49 citations
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September 2008 in “International journal of pharmaceutics” Artificial sebum L closely mimics human sebum for drug delivery research.
47 citations
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December 2003 in “Journal of Investigative Dermatology” DS cells in hair follicles can help form and restore hair, especially in hair loss conditions.
46 citations
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October 2012 in “Seminars in reproductive medicine” Genetic defects in androgen production are linked to male developmental disorders and are improving treatment understanding.
44 citations
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August 2004 in “Journal of Investigative Dermatology” A gene deletion in DSG4 causes sparse hair in some Pakistani families.
43 citations
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July 2003 in “Andrology” Hormonal male contraception is effective and could be market-ready, but more research is needed to ensure safety for all ethnic groups.
39 citations
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January 2015 in “Annals of dermatology/Annals of Dermatology” Three new types of a skin blistering disease were found, caused by specific gene mutations.
35 citations
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August 2009 in “Differentiation” Desmoglein 4 is controlled by specific proteins that affect hair growth.
35 citations
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May 2006 in “Journal of Investigative Dermatology” Monilethrix involves multiple genes affecting hair structure, including DSG4 mutations.