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research Low-Dose Dimethyl Sulfoxide (DMSO) Suppresses Androgen Receptor (AR) and Its Splice Variant AR-V7 in Castration-Resistant Prostate Cancer (CRPC) Cells

August 2025 in “Therapeutics”

Low-dose DMSO may help treat castration-resistant prostate cancer by reducing key cancer cell receptors.

Ubiquitomics of CYLD-Deficient Skin Tumors Reveals Dysregulation of Hair Follicle Keratinocyte Processes

research O02 Ubiquitomics of CYLD-deficient skin tumours reveals dysregulation of hair follicle keratinocyte processes

May 2024 in “British journal of dermatology/British journal of dermatology, Supplement”

CYLD deficiency in skin tumors disrupts hair follicle cell processes and protein secretion.

research Expanding the Nude SCID/CID Phenotype Associated with FOXN1 Homozygous, Compound Heterozygous, or Heterozygous Mutations

30 citations , January 2021 in “Journal of Clinical Immunology”

FOXN1 mutations can cause varying immune and physical issues, with severity influenced by gene activity and possibly other factors.

research Expression of CD1d in human scalp skin and hair follicles: hair cycle related alterations

16 citations , November 2005 in “Journal of Clinical Pathology”

CD1d expression in scalp skin and hair follicles changes with the hair cycle and may help protect against microbes.

research Novel in vitro culture condition improves the stemness of human dermal stem/progenitor cells

18 citations , November 2013 in “Molecules and Cells”

New culture method keeps human skin stem cells more stem-like.

research SP1 and KROX20 Regulate the Proliferation of Dermal Papilla Cells and Target the CUX1 Gene

January 2024 in “Animals”

SP1 promotes and KROX20 inhibits hair cell growth by affecting the CUX1 gene.

research Mechanism of JmjC-containing protein Hairless in the regulation of vitamin D receptor function

5 citations , September 2011 in “Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease”

Hairless protein helps control hair growth by regulating vitamin D receptor activity.

research 1α,25(OH)2-Dihydroxyvitamin D3/VDR protects the skin from UVB-induced tumor formation by interacting with the β-catenin pathway

45 citations , September 2012 in “The Journal of Steroid Biochemistry and Molecular Biology”

Vitamin D3 and its receptor help protect skin from UVB-related cancer.

Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D2 Synthase as a Multifunctional Lipocalin

research Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D2 Synthase as a Multifunctional Lipocalin

18 citations , October 2021 in “Frontiers in Physiology”

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

research 560 Isolation of an “early” transit amplifying keratinocyte population in interfollicular human epidermis: a role for CD271 receptor

November 2022 in “Journal of Investigative Dermatology”

Scientists found a new type of skin cell that could help with skin repair and these cells work better with a certain protein.

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