research Design, synthesis and structure-activity relationships studies on steroidal aromatase and 5α-reductase inhibitors as anti-tumors
Modified steroidal inhibitors showed promise in treating hormone-dependent cancers.
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630-660 / 1000+ resultsresearch Metabolic effects of 5α-reductase inhibition in humans
Dutasteride may reduce insulin sensitivity and increase body fat.
research Association of 5-α reductase inhibitors and sexual dysfunction: A RADAR report
Using hair loss drugs finasteride and dutasteride may cause sexual side effects.
research Major role for 5-alpha reductase inhibitors in the aging male
5-alpha reductase inhibitors help treat prostate issues in aging men, but their role in cancer prevention is debated.
research Faculty Opinions recommendation of Promising therapies for treating and/or preventing androgenic alopecia.
There are several promising treatments for hair loss, including dutasteride, latanoprost, ketoconazole shampoo, anti-androgens, laser/light treatment, and platelet-rich plasma, but more research is needed.
research Forum
The document concludes that various medications and treatments can have significant, sometimes adverse, effects on health outcomes.
research Re: Effect of Testosterone Supplementation With and Without a Dual 5α-Reductase Inhibitor on Fat-Free Mass in Men with Suppressed Testosterone Production: A Randomized Controlled Trial
Testosterone increases muscle mass regardless of DHT conversion blocking.
research Les Visiteurs des malades
5ARIs effectively treat and manage BPH by reducing prostate size and symptoms.
research Hair loss in women
The document concludes that hair loss in women can be treated with topical treatments or hormone therapy depending on the cause.
research Prostatakarzinom
5α-reductase inhibitors lower overall prostate cancer risk but not high-grade cancer risk; longer-term screening and new treatments show promise.
research Medical Management Options for Hair Loss
The document concluded that FDA-approved treatments like minoxidil and finasteride are effective for hair loss, while the effectiveness of natural remedies and other non-approved treatments is not well-supported by evidence.
research Urological Oncology: Prostate Cancer
Male pattern baldness may be linked to prostate cancer risk.
research Editorial Comment
Dutasteride reduces prostate cancer risk by 23% in high-risk men.
research MP-09.08
The study found that different criteria led to different patient groups in the CombAT study compared to the MTOPS study.
research Medikamentöse Therapie des benignen Prostatasyndroms (BPS)
Combination drug therapies are more effective for high-risk BPS patients but have more side effects and costs.
research Market Analysis of 5α-Reductase Inhibitor
The market for these drugs is expected to grow.
research Why would men use finasteride in 2005?
In 2005, men used finasteride mainly to treat an enlarged prostate.
research Successes and failures of evidence based urology
Evidence-based urology improved treatment and quality of life for conditions like BPH by shifting from surgery to effective medications like finasteride and dutasteride.
research Reply by the authors
Dutasteride may help prevent prostate cancer, but more research is needed.
research A4. Hair loss – surgical and pharmacological treatment
Hair loss can be treated with medications like finasteride and surgical methods like hair transplants.
research Antiandrogens
Antiandrogens block male hormones and are not safe during pregnancy.
research Bioengineered polyester nanoparticles for the synergistic treatment of androgenic alopecia via the suppression of 5α-reductase and knockdown of androgen receptor
Bioengineered nanoparticles can effectively treat hair loss by targeting specific enzymes and receptors.
research 10 Medical therapyMedical Treatment of Male and Female Pattern Hair Loss
Medical treatments like minoxidil and finasteride are important for improving hair loss and quality of life.
research A systematic review on the treatment of androgenetic alopecia
Doctors should prescribe Minoxidil, Finasteride, and Dutasteride for treating androgenetic alopecia.
research The challenging role of antiandrogens in the management of polycystic ovary syndrome
Antiandrogens are used to manage polycystic ovary syndrome by reducing androgen levels or controlling their effects, often combined with lifestyle changes and other treatments.
research Faculty Opinions recommendation of Post-finasteride syndrome: a surmountable challenge for clinicians.
Clinicians need to better understand and treat Post-finasteride syndrome.
research A preliminary result of adipose derived stem cell treatment for female pattern hair loss
Stem cell treatment improved hair density in female hair loss patient.
research Update Treatment of Male Androgenetic Alopecia
The best treatment for male pattern baldness is a combination of topical minoxidil and oral finasteride.
research Management of androgenetic alopecia: a review
Combination therapies are more effective for treating androgenetic alopecia than single treatments.
research Sulfotransferase SULT1A1 activity in hair follicle, a prognostic marker of response to the minoxidil treatment in patients with androgenetic alopecia: a review
Sulfotransferase SULT1A1 activity may predict minoxidil treatment success for hair loss.