225 citations
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April 2018 in “Journal of Investigative Dermatology” Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.
220 citations
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March 2020 in “Advanced functional materials” Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.
212 citations
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May 2012 in “Genes & Development” Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.
211 citations
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April 2013 in “Development” More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.
191 citations
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September 2011 in “Cell stem cell” Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.
184 citations
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November 2014 in “Developmental Cell” Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.
175 citations
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December 2014 in “PLoS Biology” Macrophages help activate hair follicle stem cells, affecting hair growth and skin repair.
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September 2001 in “European Journal of Cancer Care” Chemotherapy-induced hair loss significantly affects patients' well-being, and nurses are key in helping them cope, but more research is needed to find effective treatments.
157 citations
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May 2021 in “Endocrine Reviews” Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.
149 citations
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July 2017 in “PLoS Biology” Hair follicle patterns form through a mix of self-organization and signaling interactions.
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June 2012 in “PLoS ONE” Paneth cells help support stem cells and aid tissue regeneration after injury.
144 citations
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September 2012 in “Genes & development” Aging causes skin stem cells to work less effectively.
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September 2020 in “Journal of neurophysiology” Young adults have about 230,000 tactile nerve fibers, decreasing 5-8% per decade with age.
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May 2019 in “Cells” Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.
135 citations
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December 2015 in “Expert Opinion on Biological Therapy” Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.
132 citations
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January 2017 in “International Journal of Molecular Sciences” Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
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August 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects” TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.
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October 1995 in “Journal of the American Academy of Dermatology” Electrolysis is effective for permanent hair removal, but technique is key to avoid scarring, and sometimes hormonal treatment is needed for women with hirsutism.
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November 2017 in “Frontiers in Immunology” The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.
126 citations
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January 1987 in “Journal of The American Academy of Dermatology” The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.
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June 2020 in “Cell Stem Cell” Fat cells in the skin help start healing and form important repair cells after injury.
123 citations
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November 2012 in “Stem cells” MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.
119 citations
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March 2020 in “Frontiers in Bioengineering and Biotechnology” Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.
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May 2015 in “European journal of pharmaceutics and biopharmaceutics” The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.
112 citations
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May 2020 in “Nature Communications” Adult fibroblasts help heart cells mature and improve heart function.
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January 2011 in “Frontiers in Systems Neuroscience” Choosing the right model order in brain connectivity analysis can affect the detection of differences between healthy individuals and those with seasonal affective disorder.
106 citations
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July 2013 in “Advances in wound care” UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.
105 citations
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January 2010 in “Mediators of Inflammation” Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.
101 citations
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July 2021 in “Nature Communications” 4D polycarbonate scaffolds show promise for soft tissue repair due to their biocompatibility, shape memory, and minimal immune response.
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September 2017 in “Analytica Chimica Acta” Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.