research Cardiovascular toxicity of minoxidil in the marmoset
High doses of minoxidil can harm marmoset hearts and kidneys, possibly affecting humans similarly.
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research MINOXIDIL-HAEMODYNAMIC AND CLINICAL EXPERIENCES WITH A NEW PERIPHERAL VASODILATOR
Minoxidil helps control blood pressure but has side-effects, so it's not for everyone.
research Exploring the neural mechanisms of finasteride: a proteomic analysis in the nucleus accumbens
Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.
research Prognosis and Management of Congenital Hair Shaft Disorders without Fragility—Part II
Some congenital hair disorders improve with age and can be managed with treatments like minoxidil, retinoids, supplements, and gentle hair care, but there's no cure.
research Androgen Receptor Actions Modify Skin Structure and Chemical Carcinogen-induced Skin Cancer Susceptibility in Mice
Androgen receptor inactivation delays skin cancer onset and reduces incidence in mice, with gender differences in susceptibility.
research Trends in the Development of New Drugs for Treatment of Benign Prostatic Hyperplasia
New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.
research HYPOPIGMENTED MYCOSIS FUNGOIDES IN A CHILD SUCCESSFULLY TREATED WITH UVA1-LIGHT
UVA1-light therapy successfully treated a child's skin condition, mycosis fungoides.
research Hair Growth Promoting and Anticancer Effects of p21-activated kinase 1 (PAK1) Inhibitors Isolated from Different Parts of Alpinia zerumbet
Compounds from Alpinia zerumbet may help with hair regrowth and cancer treatment by targeting PAK1.
research The concealed side of caspases: beyond a killer of cells
Caspases do more than kill cells; they also help in cell growth and disease, and targeting them could lead to new treatments.
research Finasteride and androgenic alopecia; from therapeutic options to medical implications
Finasteride can treat hair loss, but may have side effects; evaluate and inform patients of risks.
research Structure optimization of tetrahydropyridoindole-based aldose reductase inhibitors improved their efficacy and selectivity
Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.
research Technical Procedures for Preparation and Administration of Platelet-Rich Plasma and Related Products: A Scoping Review
The review found that the way Platelet-Rich Plasma is made varies a lot, which can change the results of medical treatments.
research Development and evaluation of antisense shRNA-encoding plasmid loaded solid lipid nanoparticles against 5-α reductase activity
The new particle system could be a promising treatment for diseases related to the 5-α reductase enzyme.
research DPSCs and SHED in Tissue Engineering and Regenerative Medicine
DPSCs and SHED have great potential for medical treatments and tissue repair.
research Interventional studies for polycystic ovarian syndrome in children and adolescents
Early treatment and lifestyle changes are important for managing PCOS in young people to prevent long-term health issues.
research The use of cyproterone acetate/ethinyl estradiol in hyperandrogenic skin symptoms – a review
Cyproterone acetate with ethinyl estradiol is effective for treating skin symptoms related to high androgen levels, like in PCOS.
research Nongenomic effects of 1α,25-dihydroxyvitamin D 3 on cartilage formation deduced from comparisons between Cyp27b1 and Vdr knockout mice
1α,25-dihydroxyvitamin D3 directly affects cartilage growth and development.
research Acne and hirsuties in teenagers
Acne and increased body hair in teenage girls are normal but severe cases may need hormone evaluation and treatment can prevent diabetes linked to PCO.
research Gene profile analysis of colorectal cancer cell lines by cDNA macroarray
Colorectal cancer's ability to spread is due to changes in many genes, not just one.
research Hyperadrenocorticism Associated with Sex Steroid Excess
Dogs with sex hormone imbalances may not drink or pee a lot but often lose hair on their body and can have reproductive system issues.
research HA Filler Injection and Skin Quality–Literature Minireview and Injection Techniques
Hyaluronic acid filler injections are a favored non-surgical method to improve facial aging signs due to their convenience, effectiveness, and durability.
research Clinical Development of Topoisomerase-Interactive Drugs
New drugs targeting DNA enzymes show promise for cancer treatment but have side effects like immune system suppression and hair loss.
research Targeting the stem cell niche: role of collagen XVII in skin aging and wound repair
Collagen XVII is important for skin aging and wound healing.
research Modulation of macrophage functions by ECM-inspired wound dressings – a promising therapeutic approach for chronic wounds
ECM-inspired wound dressings can help heal chronic wounds by controlling macrophage activity.
research Topical L‐thyroxine: The Cinderella among hormones waiting to dance on the floor of dermatological therapy?
Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.
research Microemulsions as Carriers for Therapeutic Molecules
Microemulsions could improve how drugs are delivered and absorbed in the body.
research CUTANEOUS MASTOCYTOSIS IN CHILDREN: AN INDIAN EXPERIENCE
Fox Fordyce disease can occur in prepubertal girls and may be underdiagnosed.
research The Wound Microbiome
The document concludes that better understanding the wound microbiome can improve chronic wound care by preserving helpful bacteria and targeting harmful ones.
research A machine learning and network framework to discover new indications for small molecules
A machine learning model called CATNIP can predict new uses for existing drugs, like using antidepressants for Parkinson's disease and a thyroid cancer drug for diabetes.
research Self-Assembly of Solubilized Human Hair Keratins
Human hair keratins can form stable nanofiber networks that might help in tissue regeneration.