134 citations
,
January 2011 in “Development” Adam10 enzyme is crucial for healthy skin and proper Notch signaling.
133 citations
,
July 2006 in “International Journal of Dermatology” The cream effectively and safely reduces facial hair in women.
132 citations
,
April 2021 in “Stem Cell Research & Therapy” A special membrane with cell particles helps heal diabetic wounds faster.
132 citations
,
July 2000 in “Lupus” In Italian patients with lupus, the most common skin issue was chronic cutaneous lupus, especially discoid lesions, and nonspecific skin problems occurred in about a third of those with systemic lupus, mainly during active disease.
132 citations
,
November 1998 in “Journal of the American Academy of Dermatology” Topical sensitizers have mixed success in treating alopecia areata.
132 citations
,
October 1995 in “Journal of the American Academy of Dermatology” Electrolysis is effective for permanent hair removal, but technique is key to avoid scarring, and sometimes hormonal treatment is needed for women with hirsutism.
131 citations
,
August 2004 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.
131 citations
,
November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.
130 citations
,
January 1994 in “Differentiation” Mouse hair follicle cells briefly grow during the early hair growth phase, showing that these cells are important for starting the hair cycle.
130 citations
,
August 2020 in “Drug Design Development and Therapy” Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.
130 citations
,
January 2017 in “International journal of nanomedicine” Silver nanoparticles coated with substances like PEG showed strong antibacterial effects and improved wound healing when used in hydrogels.
130 citations
,
March 2014 in “Proceedings of the National Academy of Sciences of the United States of America” Epidermal Wnt/β-catenin signaling controls fat cell formation and hair growth.
130 citations
,
February 2005 in “Proceedings of the National Academy of Sciences” Corneal cells can transform into skin and hair cells through specific signals.
130 citations
,
January 2005 in “American Journal of Clinical Dermatology” Eating disorders like anorexia and bulimia cause skin problems, and dermatologists can help detect these disorders early for better treatment outcomes.
130 citations
,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).
129 citations
,
July 2019 in “Stem Cell Research & Therapy” Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.
129 citations
,
May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
129 citations
,
February 2006 in “Andrology” Men with low testosterone should be carefully evaluated and monitored before and during treatment.
128 citations
,
February 1992 in “British Journal of Dermatology” Basal cell carcinomas likely originate from hair follicle cells or stem cells.
128 citations
,
January 2023 in “Frontiers in Endocrinology” Individualized treatment and support can help most couples with recurrent implantation failure achieve pregnancy.
128 citations
,
September 2013 in “Journal of Clinical Epidemiology” The conclusion is that the risk of losing significance in meta-analysis results increases with smaller effects and more missing data, and using the median standard deviation for imputation is recommended.
128 citations
,
October 2011 in “Development” Activating a protein called β-catenin in adult skin can make it behave like young skin, potentially helping with skin aging and hair loss.
128 citations
,
July 2009 in “International Journal of Pharmaceutics” PEVs improve minoxidil skin penetration, increasing hair growth.
128 citations
,
December 2018 in “Archives of Agronomy and Soil Science” Mycorrhizal fungi help trifoliate orange plants grow better roots and adapt to drought by changing hormone levels.
128 citations
,
March 1996 in “Journal of Investigative Dermatology” 128 citations
,
March 1989 in “Experimental Cell Research” Hoxc13 is important for hair and tongue development by controlling hair keratin genes.
127 citations
,
June 2006 in “International Journal of Pharmaceutics” Liposomes and niosomes improve finasteride delivery for hair loss treatment.
127 citations
,
July 2002 in “EMBO journal” Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.
126 citations
,
January 1987 in “Current topics in developmental biology/Current Topics in Developmental Biology” Different keratin proteins are expressed in various epithelial cells at different stages, affecting cell structure and function.
125 citations
,
December 2016 in “Molecules” Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.