July 2024 in “Journal of Investigative Dermatology” Reactive lipids from aging cells change the extracellular matrix, affecting cell function and inflammation.
June 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” FGF9 from certain cells can trigger new hair growth during wound healing, but humans have fewer of these cells, which may limit hair regrowth.
September 2017 in “Journal of Investigative Dermatology” Activating the hexosamine pathway can improve skin health and increase hair follicle stem cells.
2 citations
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January 2022 in “Oxidative Medicine and Cellular Longevity” Exosomes from dermal papilla cells help hair follicle stem cells grow and survive.
36 citations
,
May 2016 in “Biomaterials” Endo-HSE helps grow hair-like structures from human skin cells in the lab.
September 2016 in “Journal of dermatological science” Epidermal stem cells use integrin β1 and α6 as markers and CD271+ cells help maintain skin health and heal wounds.
19 citations
,
February 2008 in “Archives of Dermatological Research” Mast cells might contribute to hair loss by causing skin thickening.
October 2022 in “Regenerative Biomaterials” A special gel with stem cells can create new hair follicles.
105 citations
,
December 1998 in “Archives of Dermatological Research” Dermal papilla cells mainly drive blood vessel growth in hair follicles.
31 citations
,
December 2016 in “Anais Brasileiros de Dermatologia” DHEA reduction may be linked to frontal fibrosing alopecia, but more research is needed.
17 citations
,
December 2019 in “Stem Cell Research & Therapy” Grouping certain skin cells together activates a growth pathway that helps create new hair follicles.
January 2018 in “Belarusian State Pedagogical University repository (Belarusian State Pedagogical University)” Adipose-derived stem cells can be used to create cells that help grow new hair.
8 citations
,
April 2009 in “International journal of oncology” Hair follicle cells resist turning into skin cells.
April 2017 in “Journal of Investigative Dermatology” Deleting the CRIF1 gene in mice disrupts skin and hair formation, certain proteins affect hair growth, a new compound may improve skin and hair health, blood cell-derived stem cells can create skin-like structures, and hair follicle stem cells come from embryonic cells needing specific signals for development.
April 2018 in “Journal of Investigative Dermatology” Researchers found that the Leptin receptor is a consistent marker for hair follicle dermal cells, which may help future hair research.
46 citations
,
August 2012 in “Experimental Dermatology” Engineered skin can grow chimeric hair follicles only with mouse dermal papilla cells.
December 2016 in “Paleontological Journal” Hair growth can be induced by transplanting certain cells, but these cells lose their properties during culturing. The best cell interaction happens in a liquid medium under gravity, and using collagen doesn't help. Future research could focus on using growth factors to stimulate these cells.
August 2013 in “International Wound Journal” Non-hairy skin cells might be used to regenerate hair, helping with baldness and skin wounds.
7 citations
,
March 2021 in “Biology” Scaffold improves hair growth potential.
April 2017 in “Journal of Investigative Dermatology” Dermal lymphatic vessels help hair growth by affecting hair cycle phases.
January 2023 in “Journal of cosmetic dermatology” The synthetic retinoid EC23 thickens skin and promotes hair growth more effectively and with a lower dose than natural retinoids.
November 2022 in “Journal of Investigative Dermatology” DermaCult™ Keratinocyte Expansion Medium allows human skin cells to grow longer while keeping their ability to develop properly.
20 citations
,
January 2013 in “Plastic & Reconstructive Surgery” The new device safely and effectively rejuvenates skin, making it thicker and healthier.
October 2012 in “Journal of Dermatological Science” Erythropoietin can promote hair growth by increasing IGF-1 in hair cells.
11 citations
,
April 1993 in “PubMed” Human hair cells can change based on their environment, especially interactions with certain skin cells.
April 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” Older mice heal wounds without scars due to special fibroblasts.
114 citations
,
October 1996 in “Dermatologic clinics” Hair loss is mainly caused by hormones, autoimmune issues, and chemotherapy, and needs more research for treatments.
42 citations
,
February 2017 in “Scientific Reports” Researchers found a way to create cells from stem cells that act like human cells important for hair growth and could be used for hair regeneration treatments.
29 citations
,
April 2020 in “Journal of Tissue Engineering and Regenerative Medicine” The experiment showed that human skin grown in the lab started to form early hair structures when special cell clusters were added.
Older women's scalp cells show changes that could contribute to hair thinning.