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Xinyang Tablet improves heart function in sepsis by reducing inflammation.

R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.

Ishige sinicola extract may help prevent muscle atrophy through its antioxidant and anti-inflammatory effects.

A variant in the ADAM17 gene causes hair loss by increasing protein degradation through TRIM47.

PROTAC technology shows promise for cancer treatment but needs more effective E3 ligase recruiters.

PROTACs offer new ways to treat hard-to-target diseases, with promising drugs for cancer in advanced trials.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

Targeted protein degraders show promise in treating cancer but need to target more diverse proteins.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

NEDD4 and NEDD4L help control intestinal stem cells and prevent tumors by breaking down the LGR5 receptor.

Protein ubiquitylation is crucial for controlling stem cell functions and could be targeted for cancer treatment.

Different STUB1 gene mutations cause varied symptoms in autosomal recessive ataxias.

The ubiquitin-mediated proteolysis pathway is crucial for hair follicle development in cashmere goats.

Colchicine can inhibit hair growth by affecting cell activity and protein expression in hair follicles.

OsUEV1B protein is essential for controlling phosphate levels in rice.

Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.

The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.

Smad-4 and Smad-7 are key in hair follicle development, with other Smads being less important.

PROTACs offer a new, precise way to treat cancer by breaking down harmful proteins.

New treatments targeting androgen receptors show promise for drug-resistant prostate cancer.

Newly designed proteins can effectively degrade specific proteins in cells, offering a potential new therapy method.

PROTACs show promise for cancer treatment, but designing them effectively is challenging.

Key genes and pathways involved in thyroid eye disease were identified, aiding potential treatment and diagnosis.

Blocking a specific enzyme can reduce the negative impact of stress hormones on hair growth cells.

The Siah1 and Siah2 genes are active in mouse skin development and hair growth, especially right after birth.

The study found that sweat glands normally suppress immune responses, but this is disrupted in certain skin diseases, possibly contributing to their development.

Researchers created human cells that can turn into sebocytes, which may help study and treat skin conditions like acne.

Certain miRNAs might be involved in a hair loss condition called frontal fibrosing alopecia and could possibly help in its diagnosis.

Finasteride helps female-pattern hair loss.

MEGA PROTAC improves prediction and ranking of protein complexes better than existing methods.