160 citations
,
March 2009 in “Seminars in Cutaneous Medicine and Surgery” New insights show Lichen Planopilaris is a rare, scarring hair loss condition, hard to treat, mainly affecting middle-aged women, and significantly impacts mental health.
131 citations
,
August 2000 in “International Journal of Dermatology” Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.
122 citations
,
June 2002 in “Genes & Development” Keratin 17 is crucial for early hair strength and cell survival.
109 citations
,
October 2007 in “American Journal of Human Genetics” Giving a special protein to dogs with a certain genetic disease improved their symptoms but didn't help with hair growth.
80 citations
,
March 2000 in “Journal of cutaneous pathology” The VVG stain effectively differentiates scar tissue from normal skin and helps classify types of permanent alopecia.
75 citations
,
August 2018 in “Biochemical pharmacology” Targeting the skin's endocannabinoid system could help treat skin disorders.
55 citations
,
September 2014 in “Development” Wnt, Eda, and Shh pathways are crucial for different stages of sweat gland development in mice.
51 citations
,
February 2006 in “Clinics in Dermatology” Pregnant women often experience skin and hair changes, with over half getting stretch marks and pigment changes, and should be cautious with cosmetic procedures due to potential risks.
47 citations
,
September 2016 in “Reviews in endocrine and metabolic disorders” The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
44 citations
,
October 2017 in “British Journal of Dermatology” Botulinum toxin has potential for treating various skin conditions and improving wound healing.
44 citations
,
July 2011 in “Dermato-endocrinology” Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.
44 citations
,
November 2009 in “Archives of Dermatology” CYLD mutations cause a variety of skin tumors with symptoms starting around age 16, and treatments are currently limited.
42 citations
,
October 2012 in “Dermatologic Clinics” Trichoscopy is a useful tool for diagnosing different hair and scalp diseases without surgery.
41 citations
,
September 1991 in “Medical hypotheses” Prolactin may be important for skin growth and immune function.
39 citations
,
March 2008 in “Growth hormone & IGF research” Raspberry ketone may help grow hair and improve skin elasticity.
30 citations
,
March 2015 in “Journal of Dermatology” Hair thickness differences help diagnose hair loss severity.
29 citations
,
December 2017 in “International Journal of Dermatology” People with alopecia areata often have lower vitamin D levels, which are linked to more severe and longer-lasting hair loss, but vitamin D receptor levels in the skin don't show the same pattern and don't predict treatment success.
26 citations
,
August 2013 in “Australasian Journal of Dermatology” Certain scalp patterns can indicate the severity and activity of hair loss in Turkish alopecia patients.
23 citations
,
April 2018 in “Journal der Deutschen Dermatologischen Gesellschaft” Permanent hair loss from cicatricial alopecia is treated by reducing inflammation and managing symptoms, but regrowth in scarred areas is unlikely.
21 citations
,
March 2018 in “Experimental Dermatology” The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.
20 citations
,
October 2013 in “British Journal of Dermatology” The document concludes that clinicians should be aware of common hair and scalp disorders in women of African descent and that more research is needed to develop effective treatments.
16 citations
,
July 2021 in “Histopathology” New markers and pathways have been found in skin tumors, helping better understand and diagnose them.
16 citations
,
July 2012 in “Current pharmaceutical biotechnology” New treatments for skin conditions related to the sebaceous gland are being developed based on current research.
14 citations
,
April 2014 in “Medical Clinics of North America” The document concludes that quick referral and appropriate treatments are crucial for managing common skin conditions and preventing permanent damage.
12 citations
,
June 2019 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” Proper skin toxicity management in chemotherapy is key to continuing treatment and keeping patient quality of life high.
12 citations
,
October 1995 in “The Journal of Clinical Endocrinology & Metabolism” Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.
11 citations
,
February 2022 in “Scientific Reports” CD26+ fibroblasts improve skin healing and integration better than CD26− fibroblasts.
9 citations
,
July 2018 in “International Journal of Dermatology” White and yellow dots indicate severe female hair loss in dark skin.
9 citations
,
September 2009 in “Journal of Cutaneous Medicine and Surgery” UV light causes skin color loss in bald areas; wear a cap and use sunscreen.
9 citations
,
February 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” The document concludes that the human keratin gene cluster is complex, with a need for updated naming to reflect over 50 functional genes important for hair and skin biology.