4 citations
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July 2025 in “Organoids” Organoids can revolutionize medicine by modeling diseases and aiding in personalized treatments.
January 2025 in “Health engineering.” Combining stem cells and organoids could improve skin regeneration treatments.
March 2024 in “Biomedicines” Mesenchymal stem cells show promise for effective skin repair and regeneration.
425 citations
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June 2020 in “Nature” Scientists created human skin with hair from stem cells, which could help treat hair loss and skin conditions.
192 citations
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January 2018 in “Burns & Trauma” Current skin substitutes help heal severe burns but don't fully replicate natural skin features.
129 citations
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July 2019 in “Stem Cell Research & Therapy” Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.
112 citations
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January 2004 in “The International journal of developmental biology” Feather patterns form through genetic and epigenetic controls, with cells self-organizing into periodic patterns.
105 citations
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October 2017 in “Stem cells” Wnt signaling is crucial for skin development and hair growth.
72 citations
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November 2017 in “Journal of developmental biology” The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.
51 citations
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August 2013 in “The Journal of experimental medicine/The journal of experimental medicine” Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
47 citations
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July 2023 in “Nature Genetics” 46 citations
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August 2022 in “Animals” miR-144-y and FOXO3 play key roles in skin and feather development in Zhedong White geese.
46 citations
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May 2003 in “Mechanisms of Development” Increasing calcium sensing receptor speeds up skin and hair development in mice.
40 citations
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November 2021 in “International Journal of Molecular Sciences” Mutant keratins cause inflammation in Epidermolysis Bullosa Simplex, suggesting targeting them could help treat the disorder.
39 citations
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March 2009 in “Dermatology Online Journal” Understanding EGFR roles could lead to new hair loss treatments.
37 citations
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June 2019 in “Stem cells” Special particles from skin cells can promote hair growth by activating a specific growth signal.
37 citations
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May 2018 in “Frontiers in physiology” Certain RNA molecules are important for the development of wool follicles in sheep.
33 citations
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August 2008 in “American Journal Of Pathology” Hedgehog signaling is essential for normal sebaceous gland development and affects keratin 6a expression.
31 citations
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August 2021 in “Stem Cell Research & Therapy” The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
29 citations
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January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” P-cadherin is crucial for hair follicle pigmentation but not skin pigmentation.
23 citations
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October 2021 in “Cell Stem Cell” Hair thinning causes stem cell loss through a process involving Piezo1, calcium, and TNF-α.
22 citations
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August 2020 in “Cells” TGM3 is important for skin and hair structure and may help diagnose cancer.
20 citations
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November 2014 in “Developmental Dynamics” Palate formation and skin healing share similar biological processes.
18 citations
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June 2018 in “Journal of Dental Research” Msx2 is essential for proper enamel formation by preventing abnormal cell transformation.
16 citations
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December 2020 in “PloS one” Researchers found WNT10A to be a key gene in developing goat hair follicles.
16 citations
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May 2015 in “Tissue Engineering Part C-methods” A two-step method was created in 2015 to make more cells that help with hair growth, but they need to be combined with other cells for 4 days to actually form new hair.
14 citations
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March 2016 in “Mechanisms of Development” Basonuclin 2 is vital for the development of facial bones, hair follicles, and male germ cells in adult mice, and its absence can lead to dwarfism and abnormal follicles.
13 citations
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March 2024 in “Cell Transplantation” Engineered skin tissue is a promising tool for safer cosmetic testing.
12 citations
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March 2022 in “Development” Mechanical forces are crucial in shaping our sensory organs during development.
12 citations
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August 2007 in “Human Molecular Genetics” Lymphotoxin-β is crucial for proper skin development in embryos.