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The research suggests that a specific skin gene can be controlled by signals within and between cells and is wrongly activated in certain skin diseases.

Alopecia areata involves unique activation of certain immune cells.

Some new isatin compounds could be strong cancer-fighting drugs because they fit well in cancer-related proteins and have good drug-like properties.

Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.

Activated β-catenin affects hair growth and skin thickness, and changes are reversible.

A mutation in the EDNRA gene causes Oro-Oto-Cardiac syndrome, affecting face and heart development.

Four-amino acid part makes enzyme sensitive to finasteride.

A JAK1 variant causes hair loss, skin issues, and thyroid disease, but treatment with a specific inhibitor can help.

AP-1 and TGFß work together to drive resistance in basal cell carcinoma, suggesting new treatment options.

A new mutation in the PLEC gene causes a rare condition with skin blistering, muscle weakness, and hair loss.

SSEA-4 can distinguish between eccrine and apocrine sweat gland ducts.

Id2 gene helps keep hair follicle stem cells inactive.

Upadacitinib may effectively treat twenty-nail dystrophy without causing pain.

High ODC and low K1 and K10 may indicate early skin tumors in mice.

Janus Kinase inhibitors are effective and have an acceptable safety profile for treating moderate to severe Ulcerative Colitis.

Androgen receptor activity is influenced by hormones, co-factors, modifications, and mutations.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.

A man with Acrodermatitis continua did not get better with etanercept treatment, and his condition worsened, suggesting treatment effectiveness may vary by genetics and race.

Blocking a certain signal in the gp130 receptor can improve tissue healing and lessen osteoarthritis symptoms.

ARQ-234, a protein designed to treat atopic dermatitis, shows increased effectiveness in early testing.

A peptide known for reducing wrinkles also effectively inhibits an enzyme linked to skin inflammation and acne.

Activating Nrf2 helps wounds heal faster by increasing hair follicle stem cells.

Dexamethasone increases the activity of androgen receptors in human skin cells, which may link it to certain types of hair loss.

Dermal fibroblasts have adjustable roles in wound healing, with specific cells promoting regeneration or scar formation.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

Certain drugs increase calcium levels in cancer cells by triggering internal calcium release.

Eccrine gland activity may be linked to alopecia areata.

Certain genetic variants impair enzyme activity, contributing to non-classic congenital adrenal hyperplasia.