research Stem cells in tissues, organoids, and cancers
Stem cells are crucial for tissue growth, cancer treatment, and disease modeling, but challenges remain in clinical use.
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research Proinflammatory cytokines regulate epidermal stem cells in wound epithelialization
Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.
research Management of primary cicatricial alopecias: options for treatment
There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.
research Disruption of Smad4 in Mouse Epidermis Leads to Depletion of Follicle Stem Cells
Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.
research Skin-permeable liposome improved stability and permeability of bFGF against skin of mice with deep second degree scald to promote hair follicle neogenesis through inhibition of scar formation
A new liposome treatment helps heal deep burns on mice by improving hair regrowth and reducing scarring.
research Intrinsic activation of cell growth and differentiation in ex vivo cultured human hair follicles by a transient endogenous production of ROS
Temporary ROS production in cultured human hair follicles promotes growth and stem cell activation.
research Obesity and peri-implantation endometrium
Obesity negatively affects the endometrium, leading to higher miscarriage risk and impaired cell function.
research A family business: stem cell progeny join the niche to regulate homeostasis
Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.
research Stem Cells and their Niches
The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.
research Biology of the Hair Follicle: The Basics
The document concludes that understanding hair follicle biology can lead to better hair loss treatments.
research Bioengineering a 3D integumentary organ system from iPS cells using an in vivo transplantation model
Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.
research Role of bulge epidermal stem cells and TSLP signaling in psoriasis
Blocking TSLP reduces skin inflammation and cell overgrowth in psoriasis.
research MULTIOMICS – A NEW EXCITING ERA OF RESEARCH
Multiomics is revolutionizing biology by enabling breakthroughs in research and disease diagnosis.
research WEWNĄTRZNACZYNIOWA TROMBOLIZA I TROMBEKTOMIA TĘTNICY PŁUCNEJ
Pulmonary artery thrombectomy is safe and effective but not widely used.
research Stem Cells in the Skin
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
research The Use of Adipose-Derived Stem Cells in Selected Skin Diseases (Vitiligo, Alopecia, and Nonhealing Wounds)
Adipose-derived stem cells show promise in treating skin conditions like vitiligo, alopecia, and nonhealing wounds.
research A matter of life and death: self‐renewal in stem cells
Stem cell self-renewal is complex and needs more research for full understanding.
research Immunopathogenesis of Primary Cicatricial Alopecia
Hair loss in Lichen Planopilaris is caused by immune system issues damaging hair follicles and stem cells.
research Tissue engineering of human hair follicles using a biomimetic developmental approach
Researchers created human hair follicles using a new method that could help treat hair loss.
research Stretching the limits: from homeostasis to stem cell plasticity in wound healing and cancer
Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.
research Corticosterone inhibits GAS6 to govern hair follicle stem-cell quiescence
Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.
research Next generation human skin constructs as advanced tools for drug development
Advanced human skin models improve drug development and could replace animal testing.
research Advanced nanocarrier- and microneedle-based transdermal drug delivery strategies for skin diseases treatment
Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
research Strategies to enhance epithelial–mesenchymal interactions for human hair follicle bioengineering
Improving the environment and cell interactions is key for creating human hair in the lab.
research Human Hair Follicle: An Update on Biology and Perspectives in Hair Growth Disorders Treatment
New treatments for hair growth disorders are needed due to limited current options and complex hair follicle biology.
research Hair follicle stem cell progeny heal blisters while pausing skin development
Skin healing from blisters can delay hair growth as stem cells focus on repairing skin over developing hair.
research Lgr5 marks cycling, yet long-lived, hair follicle stem cells
Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.
research In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators
Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.
research Signaling in the stem cell niche: regulating cell fate, function and plasticity
The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.
research Epidermal Development in Mammals: Key Regulators, Signals from Beneath, and Stem Cells
Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.