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Three-Dimensional Imaging of Tight Junction Network Across Multiple Layers of Human Epidermis by Array Tomography Using Backscattered Electron-Mode Scanning Electron Microscopy

research LB1081 Three-dimensional imaging of tight junction-network across multiple layers of human epidermis by array tomography using backscattered electron-mode scanning electron microscopy

August 2019 in “Journal of Investigative Dermatology”

The study found that tight junctions reach the top layer of the skin's stratum granulosum, not just the second top layer as previously thought.

research The Localization of Label-Retaining Cells in Eccrine Glands

28 citations , January 2009 in “Journal of Investigative Dermatology”

Stem cells in eccrine glands could be used for regenerative medicine.

research Histochemical observations of lectin-binding sites and keratin distribution in calcifying epithelioma of Malherbe.

6 citations , January 1985 in “ACTA HISTOCHEMICA ET CYTOCHEMICA”

Tumor cells in calcifying epithelioma of Malherbe resemble hair follicle cells.

research Keratin expression in the normal nail unit: markers of regional differentiation

119 citations , January 2000 in “British Journal of Dermatology”

Different parts of the nail express different keratins, showing unique patterns of differentiation.

research Comparison of two in vitro models for the analysis of follicular penetration and its prevention by barrier emulsions

33 citations , February 2009 in “European journal of pharmaceutics and biopharmaceutics”

Pig ear skin is better than human skin for testing how well barrier creams block allergens from entering hair follicles.

research Comparative Characterization of Human Meibomian Glands, Free Sebaceous Glands, and Hair-Associated Sebaceous Glands Based on Biomarkers, Analysis of Secretion Composition, and Gland Morphology

March 2024 in “International journal of molecular sciences”

Meibomian glands are highly specialized and differ significantly from other sebaceous glands in structure and function.

research Exosomes serve as a crucial mediator of epithelial–fibroblast communication during hair follicle morphogenesis in cashmere goats

November 2024 in “Comparative Biochemistry and Physiology Part D Genomics and Proteomics”

Exosomes help hair follicle development in cashmere goats.

research Generation of bioengineered feather buds on a reconstructed chick skin from dissociated epithelial and mesenchymal cells

10 citations , March 2016 in “Development Growth & Differentiation”

Scientists created feather buds in lab-grown chick skin using specific cell interactions.

research Expression Characteristics of EGF and EGFR in Developing Skin of Goat Fetus

January 2009

EGF and EGFR are essential for goat fetal skin development.

research Development of Hair Follicle Dermal Papilla Spheroids Encapsulated in Alginate Hydrogel with Extracellular Matrix Protein

November 2024

Encapsulating hair follicle cells in a special gel boosts their activity.

One-Step Generation of Core–Shell Biomimetic Microspheres Encapsulating Double-Layer Cells Using Microfluidics for Hair Regeneration

research One-step generation of core–shell biomimetic microspheres encapsulating double-layer cells using microfluidics for hair regeneration

7 citations , January 2023 in “Biofabrication”

A new method efficiently creates cell spheres that help regenerate hair.

research Proteomics Characterization of Primary Human Oral Epithelial Cells Using a Novel Culture Technique for Use in Tissue Regeneration

August 2015 in “PubMed Central”

Epithelial-derived Pop-Up Keratinocytes (ePUKs) may enhance wound healing in regenerative medicine.

research The concept of the onychodermis (specialized nail mesenchyme): an embryological assessment and a comparative analysis with the hair follicle

17 citations , January 2013 in “Journal of Cutaneous Pathology”

The onychodermis helps anchor the nail bed and may aid in nail formation.

research 454 Modeling epidermolysis bullosa simplex with cardiomyopathy using KLHL24-mutant pluripotent stem cells.

November 2025 in “Journal of Investigative Dermatology”

KLHL24-mutant stem cells help understand skin and heart disease.

research Single-cell transcriptomics defines keratinocyte differentiation in avian scutate scales

5 citations , January 2022 in “Scientific reports”

The research identified two types of keratinocytes in chicken scales: one for hard scales and another for soft skin, with similarities to human skin differentiation.

research Dynamic Behavior and Spontaneous Differentiation of Mouse Embryoid Bodies on Hydrogel Substrates of Different Surface Charge and Chemical Structures

26 citations , May 2011 in “Tissue Engineering Part A”

Hydrogel surface properties affect mouse embryoid body differentiation.

research Structure and biochemistry of mammalian hard keratin

252 citations , January 1991 in “Electron Microscopy Reviews”

research Localization of intercellular adhesion molecule-1 in middle ear cholesteatoma

13 citations , November 1995 in “European Archives of Oto-Rhino-Laryngology”

research Self Organized Skin Equivalent by Epithelial and Fibroblast Cells on Polycaprolactone Electrospun Mat with Porous Fibers

4 citations , October 2017 in “Advances in tissue engineering & regenerative medicine”

Researchers created a potential skin substitute using a biodegradable mat that supports skin cell growth and layer formation.

research Biochemical Evidence That Small Proline-rich Proteins and Trichohyalin Function in Epithelia by Modulation of the Biomechanical Properties of Their Cornified Cell Envelopes

99 citations , May 1998 in “Journal of biological chemistry/The Journal of biological chemistry”

Small proline-rich proteins and trichohyalin help make epithelial tissues tougher and more flexible.

research Analysis of the heterogeneity and complexity of murine extraorbital lacrimal gland via single-cell RNA sequencing

May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

The research mapped diverse cell types in mouse lacrimal glands, aiding understanding of gland biology and diseases.

research Parallels in signaling between development and regeneration in ectodermal organs

8 citations , January 2022 in “Current topics in developmental biology/Current Topics in Developmental Biology”

research In vitro Keratin Expression of Hair Cells

2 citations , November 1992 in “Journal of dermatology”

Hair cells grown in a lab showed specific hair proteins.

Basement Membrane Components Define the Microenvironment of Aggregated Fibroblasts in the Skin and Support Their Aggregation In Vitro

research Basement membrane components define the microenvironment of aggregated fibroblasts in the skin and support their aggregation in vitro

September 2025 in “bioRxiv (Cold Spring Harbor Laboratory)”

Basement membrane supports fibroblast aggregation, aiding hair follicle development.

research Glycerophospholipid Analysis of Eastern Red Bat (Lasiurus Borealis) Hair by Electrospray Ionization Tandem Mass Spectrometry

5 citations , February 2014 in “Journal of chemical ecology”

Eastern Red Bat hair contains various glycerophospholipids, mainly phosphatidylcholine.

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