research Cytotoxic Effect of YH239-EE and Its Enantiomer on MCF7 Cell Line
The (+) enantiomer of YH239-EE effectively kills breast cancer cells.
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300-330 / 1000+ results research Quantitative Bestimmung von kosmetischen Wirk- und Pflegesubstanzen auf dem Haar
Active agents mainly stay on the hair surface after short washes.
research Progress in the design of ascorbic acid derivative-mediated drug delivery
Ascorbic acid derivatives improve drug delivery systems.
research Progesterone and allopregnanolone enhance the miniature synaptic release of glycine in the rat hypoglossal nucleus
Progesterone and allopregnanolone increase glycine release in rat brain cells.
research Valency based novel quantitative structure property relationship (QSPR) approach for predicting physical properties of polycyclic chemical compounds
The neighborhood face index (NFI) accurately predicts properties of complex molecules.
research IONIC HAIR PROFILES OF STUDENTS FROM THE MIDDLE EAST AND MOSCOW REGION
Students from the Middle East and Moscow have different hair element levels due to their environments.
research Novel Compounds for Hair Repair: Chemical Characterization and In Vitro Analysis of Thiol Cross-Linking Agents
APA is a promising new compound for repairing damaged hair, outperforming Olaplex® in strength and elasticity.
research Emergency Wound Infection Monitoring and Treatment Based on Wearable Electrochemical Detection and Drug Release with Conductive Hydrogel
A new wearable system improves wound healing by monitoring infections and delivering precise treatment.
research Inhibitory amino acid transmitters associated with axons in presynaptic apposition to cutaneous primary afferent axons in the cat spinal cord
Presynaptic inhibition of certain nerve fibers in cats is mainly controlled by GABA and glycine.
![Verification of the Major Metabolic Oxidation Path for the Naphthoyl Group in Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTh2) Antagonist 2-(2-(1-Naphthoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetic Acid (Setipiprant/ACT-129968)](/images/research/d743d32f-3115-48ff-9697-2f2d56130701/small/14175.jpg)
research Verification of the Major Metabolic Oxidation Path for the Naphthoyl Group in Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTh2) Antagonist 2-(2-(1-Naphthoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetic Acid (Setipiprant/ACT-129968)
The document confirms the structures of major metabolites of the CRTh2 antagonist Setipiprant and identifies minor metabolites.
![Benzo[c]quinolizin-3-ones: A Novel Class of Potent and Selective Nonsteroidal Inhibitors of Human Steroid 5α-Reductase 1](/images/research/ff6e6cbe-cb9c-4d11-87ef-671d28ffd4fa/small/15506.jpg)
research Benzo[c]quinolizin-3-ones: A Novel Class of Potent and Selective Nonsteroidal Inhibitors of Human Steroid 5α-Reductase 1
Benzo[c]quinolizin-3-ones are effective nonsteroidal inhibitors of human steroid 5α-reductase 1.
research Introduction: splintering urbanism
TSPO might help treat anxiety and depression.
research Electrokinetic analysis reveals common conditioner ingredient interactions with human hair
Conditioners improve hair manageability but don't repair damage.
research Understanding the formation mechanism of drug-polymer inclusion complex by structure elucidation and theoretical calculation
The research found how certain drugs and polymers form stable complexes, which could help develop new pharmaceutical forms.
research Regulation of epidermal proliferation and hair follicle cycling by synthetic photostable retinoid EC23
The synthetic retinoid EC23 thickens skin and promotes hair growth more effectively and with a lower dose than natural retinoids.
research Skin permeation of different steroid hormones from polymeric coated liposomal formulations
Polymers increased skin permeation and stability of steroid hormones in liposomal formulations.
research Synthetic studies toward the development of novel minoxidil analogs and conjugates with polyamines
New minoxidil compounds with better water solubility were made, but their full effects and safety need more research.
research Sex‐dependent responsiveness of hippocampal neurons to sex neurosteroids: A role of Arc/Arg3.1
Sex hormones affect brain cells differently in males and females.
research Allopregnanolone, the active metabolite of progesterone protects against neuronal damage in picrotoxin-induced seizure model in mice
research 2‐Deoxy‐d ‐glucose enhances tonic inhibition through the neurosteroid‐mediated activation of extrasynaptic GABA A receptors
2-DG reduces seizures by enhancing brain inhibition through specific receptor activation.
research Strontium: A Potent and Selective Inhibitor of Sensory Irritation and Topical Anti-inflammatory
Strontium can effectively reduce skin irritation and inflammation.
research In-Vitro Anticancer Activity of Chemical Constituents from Etlingera alba Poulsen against Triple Negative Breast Cancer and in silico Approaches towards Matrix metalloproteinase-1 Inhibition
Compounds from Etlingera alba may help treat Triple Negative Breast Cancer.
research Can be Hair-Keratin a Potent Biomaterial?
research Application of XANES profiles to X-ray spectromicroscopy for biomedical specimens: Part II. Mapping oxidation state of cysteine in human hair
Perming and bleaching damage hair differently, with bleached hair having more cysteic acid in the cuticle.
research Overexpression of the 18 kDa translocator protein (TSPO) in the hippocampal dentate gyrus produced anxiolytic and antidepressant-like behavioural effects
Increasing TSPO in the brain reduces anxiety and depression.
research PEG-Immobilized Keratin for Protein Drug Sequestration and pH-Mediated Delivery
PEG and keratin scaffolds can effectively deliver protein drugs by controlling release based on pH levels.
research A Review of U.S. Patents in the Field of Organic Process Development Published during July and August 2004
The document reviews 20 U.S. patents from July and August 2004 about new drug forms, cancer treatments, aroma chemicals, statin drugs, and various chemical production methods.
research Determination of finasteride, indapamide and tiemonium methyl sulphate using surface plasmon resonance band of silver nanoparticles
research Corticosterone enhances the potency of ethanol against hippocampal long-term potentiation via local neurosteroid synthesis
Corticosterone makes ethanol more effective at blocking brain processes important for learning and memory.
research Synthesis and Evaluation of 2‘-Substituted 4-(4‘-Carboxy- or 4‘-carboxymethylbenzylidene)-N-acylpiperidines: Highly Potent and in Vivo Active Steroid 5α-Reductase Type 2 Inhibitors
Compounds 15, 20, and 25 are strong inhibitors of human steroid 5α-reductase type 2.