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GlossaryEmbryogenesis

process where a fertilized egg develops into an embryo

Embryogenesis, also known as embryonic development, is the process by which a fertilized egg (zygote) develops into a fully formed embryo. This complex process involves cell division, differentiation, and morphogenesis, where cells specialize and organize into tissues and organs. It is a critical phase in prenatal development, laying the foundation for all the body's structures and systems.

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research Transdifferentiation of corneal epithelium: evidence for a linkage between the segregation of epidermal stem cells and the induction of hair follicles during embryogenesis.

55 citations , January 2004 in “The International Journal of Developmental Biology”

Corneal cells can transform into hair-producing skin cells when exposed to certain signals.

research Survival of patchwork melanoblasts is dependent upon their number in the hair follicle at the end of embryogenesis

29 citations , June 1998 in “Developmental Biology”

More melanoblasts in hair follicles mean better survival and proper hair pigmentation.

CD10 and CD34 in Fetal and Adult Human Hair Follicles: Dynamic Changes in Their Immunohistochemical Expression During Embryogenesis and Hair Cycling

research CD10 and CD34 in fetal and adult human hair follicles: dynamic changes in their immunohistochemical expression during embryogenesis and hair cycling

25 citations , July 2008 in “British Journal of Dermatology”

CD10 and CD34 levels change during hair development and different hair growth stages, which could be important for hair regeneration treatments.

research Temporal expression and steroidal regulation of piRNA pathway genes (mael, piwi, vasa) during Silurana (Xenopus) tropicalis embryogenesis and early larval development

23 citations , April 2010 in “Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology”

The piRNA pathway genes are crucial in early development and may influence sex differentiation through hormone regulation.

research Epidermal Deletion of Rac1 Causes Stem Cell Depletion, Irrespective of whether Deletion Occurs during Embryogenesis or Adulthood

18 citations , February 2007 in “Journal of Investigative Dermatology”

Deleting Rac1 in the skin depletes stem cells and damages hair follicles.

research Hair Follicle Morphogenesis During Embryogenesis, Neogenesis, and Organogenesis

4 citations , July 2022 in “Frontiers in Cell and Developmental Biology”

The document concludes that understanding adult stem cells and their environments can help improve skin regeneration in the future.

Expression Patterns of MITF During Human Cutaneous Embryogenesis: Evidence for Bulge Epithelial Expression and Persistence of Dermal Melanoblasts

research Expression patterns of MITF during human cutaneous embryogenesis: evidence for bulge epithelial expression and persistence of dermal melanoblasts

43 citations , February 2008 in “Journal of cutaneous pathology”

Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.

research Hair follicle embryogenesis in the human. Characterization of events in vivo and in vitro.

14 citations , December 1991 in “PubMed”

The document explains how hair follicles develop in humans.

research Investigating the roles of cellular senescence in embryogenesis and aging

December 2014 in “TDX (Tesis Doctorals en Xarxa)”

Cellular senescence is crucial for normal embryonic development but contributes to aging in adults.

research Hair development and Langerhans cell migration during human embryogenesis

December 2012 in “Journal of dermatological science”

Langerhans cells and melanocytes migrate to the skin and hair follicles during early human development.

research The KRAB domain zinc finger protein, Zfp157, is expressed in multiple tissues during mouse embryogenesis and in specific cells in adult mammary gland and skin

8 citations , January 2013 in “genesis”

Zfp157 is active in many mouse tissues during development and in specific adult cells.

research Building Epithelial Tissues from Skin Stem Cells

84 citations , January 2008 in “Cold Spring Harbor Symposia on Quantitative Biology”

Skin stem cells help maintain skin health, grow hair, and heal wounds.

research The Hair Follicle: A Paradoxical Androgen Target Organ

66 citations , January 2000 in “Hormone Research in Paediatrics”

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

Fadrozole And Finasteride Exposures Modulate Sex Steroid- And Thyroid Hormone-Related Gene Expression In Silurana (Xenopus) Tropicalis Early Larval Development

research Fadrozole and finasteride exposures modulate sex steroid- and thyroid hormone-related gene expression in Silurana (Xenopus) tropicalis early larval development

60 citations , November 2009 in “General and Comparative Endocrinology”

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

research Extracellular Matrix as a Regulator of Epidermal Stem Cell Fate

57 citations , March 2018 in “International Journal of Molecular Sciences”

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

research Wound-Induced Hair Neogenesis: A Portal to the Development of New Therapies for Hair Loss and Wound Regeneration

16 citations , September 2022 in “Cold Spring Harbor Perspectives in Biology”

Wound healing can potentially regrow hair and aid in hair loss treatments.

research Ontogeny of Skin Stem Cells and Molecular Underpinnings

7 citations , July 2024 in “Current Issues in Molecular Biology”

Understanding skin stem cells and their regulation is key to improving skin healing and treating disorders.

research Ectopic sebaceous gland: a developmental anomaly

7 citations , July 2006 in “Journal of cutaneous pathology”

A 21-year-old had a rare developmental anomaly with a misplaced sebaceous gland in a hair follicle.

research Trends in Human Hair Growth and Alopecia Research

3 citations , April 1990 in “Archives of dermatology”

The book reveals diverse patterns of hair growth in different species and advancements in hair and alopecia research.

research Dermal niche signaling and epidermal stem cells

January 2019 in “Advances in stem cells and their niches”

Skin health and repair depend on the signals between skin stem cells and their surrounding cells.

research Genetic and Environmental Factors that Control Merkel Cell Development and Survival

July 2017 in “D-Scholarship@Pitt (University of Pittsburgh)”

Notch signaling stops Merkel cell development, and hair follicles help maintain them after skin injury.

Isolation and Characterization of a Fetal-Maternal Microchimeric Stem Cell Population in Maternal Hair Follicles Long After Childbirth

research Isolation and Characterization of a Fetal-Maternal Microchimeric Stem Cell Population in Maternal Hair Follicles Long after Parturition

12 citations , May 2019 in “Stem cell reviews”

Fetal-maternal stem cells in a mother's hair can help with tissue repair and regeneration long after childbirth.

research Lineage Commitment of Dermal Fibroblast Progenitors is Mediated by Chromatin De-repression

1 citations , March 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.

research Hair follicles and their role in skin health

16 citations , December 2006 in “Expert Review of Dermatology”

Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.

research Epithelial elements in superficial angiomyxomas: mimicry of adnexal development, and mesenchymal‐to‐epithelial transition

June 2025 in “Histopathology”

Epithelial elements in superficial angiomyxomas are non-neoplastic growths mimicking embryogenesis.

research Expression ofWise in chick embryos

6 citations , July 2007 in “Developmental Dynamics”

The molecule Wise is involved in the development of various structures in chick embryos.

research Resident macrophages of the lung and liver: The guardians of our tissues

4 citations , November 2022 in “Frontiers in Immunology”

Lung and liver macrophages protect our tissues and their dysfunction can cause various diseases.