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Epithelial Loss of Mitochondrial Oxidative Phosphorylation Leads to Disturbed Enamel and Impaired Dentin Matrix Formation in Postnatal Developed Mouse Incisor

research Epithelial loss of mitochondrial oxidative phosphorylation leads to disturbed enamel and impaired dentin matrix formation in postnatal developed mouse incisor

3 citations , December 2020 in “Scientific reports”

Mitochondrial problems in tooth cells lead to bad enamel and dentin development in mice.

research A Novel Androgen Receptor Gene Mutation in a 46,XY Patient: Complete Androgen Insensitivity Syndrome

1 citations , August 2015 in “AACE Clinical Case Reports”

A new gene mutation causes complete androgen insensitivity in a 16-year-old with a female appearance.

research YAP and TAZ are essential for basal and squamous cell carcinoma initiation

76 citations , June 2018 in “EMBO Reports”

YAP and TAZ proteins are necessary for the development of two types of skin cancer.

Smad1 and Smad5 but Not Smad8 Establish Stem Cell Quiescence Critical for Transforming Premature Hair Follicles During Morphogenesis to the Postnatal State

research Smad1 and 5 but Not Smad8 Establish Stem Cell Quiescence Which Is Critical to Transform the Premature Hair Follicle During Morphogenesis Toward the Postnatal State

31 citations , September 2013 in “Stem Cells”

Smad1 and Smad5 are essential for hair follicle development and stem cell sleepiness.

research ILK modulates epithelial polarity and matrix formation in hair follicles

22 citations , December 2013 in “Molecular biology of the cell”

ILK is essential for proper hair follicle development and structure.

research The Role of Histone Demethylases in Disease

1 citations , January 2011 in “Springer eBooks”

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

research MOF-mediated histone H4 Lysine 16 acetylation governs mitochondrial and ciliary functions by controlling gene promoters

1 citations , July 2023 in “Nature communications”

MOF controls key genes for skin development by regulating mitochondrial and ciliary functions.

research Bioprinting of skin constructs for wound healing

150 citations , January 2018 in “Burns & Trauma”

Bioprinting could improve wound healing but needs more development to match real skin.

research Careless talk costs lives: fibroblast growth factor receptor signalling and the consequences of pathway malfunction

119 citations , November 2014 in “Trends in Cell Biology”

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

research 9 Role of 5α-reductase in health and disease

101 citations , April 1994 in “Baillière's clinical endocrinology and metabolism”

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

research New insights into the functions of Cox-2 in skin and esophageal malignancies

54 citations , April 2020 in “Experimental & Molecular Medicine”

Cox-2 significantly contributes to the development and progression of skin and esophageal cancers.

research Epidermal Differentiation Complex: A Review on Its Epigenetic Regulation and Potential Drug Targets.

39 citations , January 2016 in “PubMed”

Understanding how EDC genes are regulated can help develop better drugs for skin diseases.

research Meis1 Regulates Epidermal Stem Cells and Is Required for Skin Tumorigenesis

29 citations , July 2014 in “PloS one”

Meis1 is crucial for skin health and tumor development.

research Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue architecture

2 citations , February 2024 in “Nature cell biology”

Mechanical forces are crucial for shaping cells and forming tissues during development.

research A direct link betweenPrss53, hair curvature, and skeletal dysplasia

February 2019 in “bioRxiv (Cold Spring Harbor Laboratory)”

The gene Prss53 affects hair shape and bone development in rabbits.

research Progress and perspectives on hydrogel-assisted skin organoids

May 2026 in “Organoid Research”

Hydrogel-based methods improve skin organoid development for medical and research applications.

research The agouti mouse model: an epigenetic biosensor for nutritional and environmental alterations on the fetal epigenome

231 citations , July 2008 in “Nutrition reviews”

Diet changes can protect against harmful environmental effects on fetal development.

research Fetal Alcohol Syndrome: Current Status of Pathogenesis

171 citations , October 1990 in “Alcoholism/Alcoholism, clinical and experimental research”

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

research Extracellular vesicle-based drug overview: research landscape, quality control and nonclinical evaluation strategies

77 citations , August 2025 in “Signal Transduction and Targeted Therapy”

Extracellular vesicles show promise for treating diseases but face challenges in development and regulation.

research Noggin overexpression inhibits eyelid opening by altering epidermal apoptosis and differentiation

65 citations , June 2003 in “EMBO journal”

Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.

research Disrupted Ectodermal Organ Morphogenesis in Mice with a Conditional Histone Deacetylase 1, 2 Deletion in the Epidermis

32 citations , June 2013 in “Journal of Investigative Dermatology”

Mice without certain skin proteins had abnormal skin and hair development.

Role of Beta-Catenin Activation Levels and Fluctuations in Controlling Cell Fate

research Role of β-Catenin Activation Levels and Fluctuations in Controlling Cell Fate

28 citations , February 2019 in “Genes”

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

research Expression of Wnt Genes in Echinaster Sepositus Arm Regeneration

2 citations , January 2018 in “International Journal of Biochemistry & Physiology”

Wnt genes help starfish regrow arms by aiding wound healing and cell development.

research Ectodysplasin-A (EDA) Signaling Cross-Talk in Skeletogenesis

March 2026 in “Calcified Tissue International”

The EDA pathway plays a key role in bone development by interacting with other signaling pathways.

research Sphingolipid metabolism orchestrates the establishment of the adult hair follicle stem cell niche to control skin homeostasis

January 2024 in “bioRxiv (Cold Spring Harbor Laboratory)”

A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.

research Genetic, hormonal and metabolic aspects of PCOS: an update

258 citations , July 2016 in “Reproductive Biology and Endocrinology”

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The Lysosomal Protease Cathepsin L Is an Important Regulator of Keratinocyte and Melanocyte Differentiation During Hair Follicle Morphogenesis and Cycling

research The Lysosomal Protease Cathepsin L Is an Important Regulator of Keratinocyte and Melanocyte Differentiation During Hair Follicle Morphogenesis and Cycling

146 citations , May 2002 in “The American journal of pathology”

Cathepsin L is essential for normal hair growth and development.

Suprabasal Desmoglein 3 Expression in the Epidermis of Transgenic Mice Results in Hyperproliferation and Abnormal Differentiation

research Suprabasal Desmoglein 3 Expression in the Epidermis of Transgenic Mice Results in Hyperproliferation and Abnormal Differentiation

108 citations , July 2002 in “Molecular and cellular biology”

Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.

Identification of a Link Between Wnt/β-Catenin Signaling and the Cell Fusion Pathway

research Identification of a link between Wnt/β-catenin signalling and the cell fusion pathway

101 citations , November 2011 in “Nature Communications”

Wnt/β-catenin signaling is crucial for cell fusion in placental development.

research 9 Pilosebaceous physiology in relation to hirsutism and acne

75 citations , May 1986 in “Clinics in endocrinology and metabolism”

Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.

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