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Liposomes improve drug delivery and reduce skin irritation in dermatology.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Testosterone's muscle-building effects do not require its conversion to DHT.

Liposomes could improve how skin care products work but are costly and not very stable.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

Nutraceuticals may improve skin health and protect against aging, but more research is needed on their optimal use and possible health risks.

Sensitive skin is often caused by nerve fibers and environmental factors, and can be managed with mild skincare and professional advice.

Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.

The yeast Pityrosporum ovale can cause skin allergies and infections, and antifungal treatments like ketoconazole are effective against it.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.

New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Human hair follicles can make and process prostaglandins, which may affect hair growth.

Finasteride effectively treats male pattern baldness, improving hair growth and density.

Beta-catenin is crucial for skin cell growth, development, and cancer formation.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.