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Finasteride raises suicide-linked aggression and stops clozapine's positive effects in schizophrenia animals.

Allopregnanolone increases KCC2 expression in baby male rats' brains, while finasteride doesn't affect it.

Diabetic neuropathy in mice is linked to poor mitochondria function and lower brain hormone production.

Reducing neurosteroid levels worsens brain injury in fetal sheep.

DHT is needed for long-term depression, while E2 is needed for full long-term potentiation in male rat brains.

Neonatal neurosteroid levels affect adult brain function and behavior.

Allopregnanolone likely doesn't influence ethanol's rewarding effects in these mice.

Allopregnanolone may help prevent nicotine withdrawal symptoms.

Estrogen and androgen signals control synaptic changes in rat brains.

Paroxetine relieves pain by increasing allopregnanolone levels.

Some common medications can harm male fertility, but many effects can be reversed.

AC-5216 reduces anxiety in mice through neurosteroids affecting GABAA receptors.

Finasteride use may lead to less alcohol consumption in men with lasting sexual side effects.

Finasteride worsens seizures in epilepsy rats and speeds up epileptogenesis in mice.

Altered metabolism can help control seizures by changing brain signaling and energy use, suggesting new treatments for epilepsy.

Progesterone's seizure-reducing effects are mainly due to allopregnanolone, not progesterone receptors.

Testosterone increases seizure risk through its conversion to specific neurosteroids.

Finasteride reduces new brain cells in male mice, possibly causing depression.

Stress worsens Tourette symptoms by increasing allopregnanolone levels.

Social isolation makes mice more sensitive to alcohol's effects on brain function.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

Medications for enlarged prostate can cause sexual side effects like reduced libido, erectile dysfunction, and ejaculatory problems.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Finasteride and dutasteride may cause depression and anxiety, especially in younger men.

Neurosteroids like neuro-estrogen and neuro-androgen are crucial for brain function and can improve cognition and protect against aging-related decline.

Sex steroids produced in the hippocampus are crucial for brain functions like memory and learning in rodents.

EETs can delay seizures by affecting GABA activity, offering potential new treatments for seizures.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

Neurosteroids may help metyrapone reduce cocaine addiction.