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Minoxidil Exerts Different Inhibitory Effects on Gene Expression of Lysyl Hydroxylase 1, 2, and 3: Implications for Collagen Cross-Linking and Treatment of Fibrosis

research Minoxidil exerts different inhibitory effects on gene expression of lysyl hydroxylase 1, 2, and 3: Implications for collagen cross-linking and treatment of fibrosis

38 citations , June 2005 in “Matrix Biology”

Minoxidil affects collagen-related genes, potentially helping treat fibrosis.

research How Does pH Fit in with Oscillating Polar Growth?

37 citations , March 2018 in “Trends in Plant Science”

pH, calcium, and reactive oxygen species regulate plant cell growth, with key roles for NADPH oxidases and plasma membrane H+-ATPases.

Body Composition Changes and Inhibition of Fat Development In Vivo Implicate Androgen in Regulation of Stem Cell Lineage Allocation

research Body composition changes and inhibition of fat development in vivo implicates androgen in regulation of stem cell lineage allocation

37 citations , June 2011 in “Journal of Cellular Biochemistry”

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

Lymphoid Enhancer-Binding Factor-1 Interacts with the DNA-Binding Domain of the Vitamin D Receptor

research Lymphoid Enhancer-binding Factor-1 (LEF1) Interacts with the DNA-binding Domain of the Vitamin D Receptor

37 citations , April 2011 in “Journal of Biological Chemistry”

LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.

research Studying SARS-CoV-2 infectivity and therapeutic responses with complex organoids

36 citations , August 2021 in “Nature Cell Biology”

Organoids can help study COVID-19 and develop treatments, but face challenges like instability and limited renewal.

Label Retaining Cells with Myoepithelial Characteristics from the Proximal Acinar Region Define Stem Cells in the Sweat Gland

research Label Retaining Cells (LRCs) with Myoepithelial Characteristic from the Proximal Acinar Region Define Stem Cells in the Sweat Gland

36 citations , September 2013 in “PLoS ONE”

Sweat gland stem cells help maintain glands, aid wound healing, and can regenerate skin structures.

Transplantation of Bone-Marrow-Derived Mesenchymal and Epidermal Stem Cells Contribute to Wound Healing with Different Regenerative Features

research Transplantation of bone-marrow-derived mesenchymal and epidermal stem cells contribute to wound healing with different regenerative features

36 citations , April 2013 in “Cell and Tissue Research”

Bone-marrow and epidermal stem cells help heal wounds differently, with bone-marrow cells aiding in blood vessel formation and epidermal cells in hair growth.

Genetically-Manipulated Adult Stem Cells as Therapeutic Agents and Gene Delivery Vehicles for Wound Repair and Regeneration

research Genetically-manipulated adult stem cells as therapeutic agents and gene delivery vehicle for wound repair and regeneration

36 citations , August 2011 in “Journal of Controlled Release”

Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.

Recent Advances on Skin-Resident Stem/Progenitor Cell Functions in Skin Regeneration, Aging, and Cancers and Novel Anti-Aging and Cancer Therapies

research Recent advances on skin‐resident stem/progenitor cell functions in skin regeneration, aging and cancers and novel anti‐aging and cancer therapies

36 citations , September 2009 in “Journal of Cellular and Molecular Medicine”

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

research The bright side of fibroblasts: molecular signature and regenerative cues in major organs

35 citations , August 2021 in “npj Regenerative Medicine”

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

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