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research Involvement of DKK1 secreted from adipose‐derived stem cells in alopecia areata

November 2023 in “Cell Proliferation”

A protein from fat-derived stem cells, DKK1, is linked to hair loss and blocking it may help treat alopecia areata.

research Innovative Reports on the Effects of Anabolic Androgenic Steroid Abuse—How to Lose Your Mind for the Love of Sport

August 2023 in “Medicina-lithuania”

Abusing steroids can damage your heart, muscles, reproductive system, liver, skin, and brain, and may increase the risk of Alzheimer's disease.

research Data from Activator Protein-1 Activity Regulates Epithelial Tumor Cell Identity

March 2023

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

research Loss of epidermal PLCg1 induced sebaceous gland hyperplasia and sparse hair

April 2017 in “Journal of dermatological science”

Removing PLCg1 from skin cells caused thicker oil glands and less hair in mice.

research The role of dutasteride in the treatment of benign prostatic obstruction and related conditions

October 2006 in “Aging Health”

Dutasteride effectively treats benign prostatic obstruction, improves urinary flow, reduces prostate size, and may prevent prostate cancer, but can cause sexual side effects.

Methylated CpG Dinucleotides in 5-Alpha Reductase 2 Gene Might Explain the Finasteride-Resistance in BPE Patients

research Methylated CpG dinucleotides in 5-α reductase 2 gene might explain the finasteride-resistance in BPE patients

July 2020 in “European urology open science”

Methylated gene parts may cause finasteride-resistance in some enlarged prostate patients.

Combination of Finasteride and Tamsulosin in the Treatment of Male Lower Urinary Tract Symptoms: What Are Patients Thinking?

research Combination of finasteride and tamsulosine in the treatment of male lower urinary tract symptoms: What patients are thinking about?

March 2018 in “European Urology Supplements”

Patients follow treatment well, but many change medicines; good information helps compliance.

research Eccrine Duct Dilation as a Marker of Cicatricial Alopecia

8 citations , September 2016 in “The American Journal of Dermatopathology”

Enlarged sweat gland ducts may indicate scarring hair loss.

research Finasteride

187 citations , January 1994 in “The New England Journal of Medicine”

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

A New Look at the 5-Alpha-Reductase Inhibitor Finasteride

research A New Look at the 5?-Reductase Inhibitor Finasteride

137 citations , March 2006 in “Cns Drug Reviews”

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

research Finasteride

86 citations , July 1993 in “Drugs”

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

Tamsulosin Treatment for Benign Prostatic Hyperplasia and Risk of Severe Hypotension in Men Aged 40-85 Years in the United States: Risk Window Analyses Using Between and Within Patient Methodology

research Tamsulosin treatment for benign prostatic hyperplasia and risk of severe hypotension in men aged 40-85 years in the United States: risk window analyses using between and within patient methodology

70 citations , November 2013 in “The BMJ”

Tamsulosin for enlarged prostate may increase the risk of severe low blood pressure, especially when starting or restarting the medication.

research Association of Benign Prostatic Hyperplasia with Male Pattern Baldness

54 citations , May 1998 in “Urology”

Men with enlarged prostates often have more severe baldness.

research Dutasteride

45 citations , January 2008 in “Drugs”

Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.

research Finasteride

40 citations , April 1999 in “Drugs”

Finasteride treats enlarged prostate, improves urinary flow, but may cause sexual side effects.

research Dutasteride: a review of current data on a novel dual inhibitor of 5alpha reductase.

38 citations , January 2005 in “PubMed”

Dutasteride effectively treats enlarged prostate with manageable side effects.

research Becker's Nevus with Ipsilateral Breast Hypoplasia: Improvement with Spironolactone

29 citations , February 2003 in “Journal of Dermatology”

Spironolactone may help enlarge a small breast linked to Becker's nevus.

research Gender Differences in Cardiac Hypertrophy

27 citations , February 2020 in “Journal of Cardiovascular Translational Research”

Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.

research Finasteride: The First 5α-Reductase Inhibitor

23 citations , July 1993 in “Pharmacotherapy”

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

research A Review on Steroidal 5α-Reductase Inhibitors for Treatment of Benign Prostatic Hyperplasia

17 citations , August 2011 in “Current Medicinal Chemistry”

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

research 5α‐Reductase Inhibitors

17 citations , November 1997 in “Andrology”

Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.