September 2017 in “Asian Journal of Beauty and Cosmetology” The Notch signaling pathway is important for hair follicle development and could help create treatments for hair disorders.
S1PR1 helps control inflammation in blood vessel cells by affecting gene activity differently in various cell types and locations.
34 citations
,
August 2016 in “Scientific Reports” Blocking TGFβ-RI signaling enhances surface ectoderm differentiation from human stem cells.
6 citations
,
January 2016 in “Journal of Stem Cell Research & Therapy” Notch1 signaling is crucial for improving wound healing and skin regeneration by affecting stem cell behavior.
18 citations
,
August 2015 in “Biochemical and Biophysical Research Communications” XEDAR triggers a specific signaling pathway in cells.
March 2016 in “Experimental Dermatology” EGFR helps hair follicles transition properly by controlling Stathmin levels.
Lhx2 is a crucial regulator of the Sonic Hedgehog signaling in early mouse retinal development.
61 citations
,
January 2011 in “PloS one” Notch signaling is essential for healthy skin and hair follicle maintenance.
January 2024 in “Wiadomości Lekarskie” Ancient immune and signaling pathways still regulate blood cell development.
8 citations
,
January 2022 in “Current topics in developmental biology/Current Topics in Developmental Biology”
March 2025 in “FEBS Journal” Epiprofin suppresses parathyroid hormone gene activity, helping regulate calcium levels and could be a treatment target for hyperparathyroidism.
6 citations
,
August 2022 in “International Journal of Molecular Sciences” EDA signaling is linked to skin disorders, various cancers, and liver disease.
32 citations
,
January 2010 in “Journal of Dermatological Science” Reduced EGFR signaling delays hair cycle and reduces fat growth, but hair development remains normal.
117 citations
,
April 2008 in “Developmental biology” Ectodysplasin inhibits Wnt signaling to help form hair follicles.
May 2000 in “Journal of Investigative Dermatology” Hedgehog signaling is crucial for hair development, cadherins affect cell adhesion, neutrophils play a role in skin lesions, and BP230 autoantibodies impact skin stability.
Epimorphin helps shape and develop epithelial cells, like those in hair follicles.
October 2025 in “Proceedings of the National Academy of Sciences” Phospholipids help plant proteins move by regulating receptor interactions.
43 citations
,
February 2013 in “Developmental dynamics” Foxi3 expression in developing teeth and hair is controlled by the ectodysplasin pathway.
161 citations
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August 2012 in “Seminars in cell & developmental biology” Hair growth and development are controlled by specific signaling pathways.
78 citations
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October 2007 in “Journal of Investigative Dermatology” Delta1 is crucial for controlling skin cell growth and preventing tumors in mice.
43 citations
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December 2006 in “The American journal of pathology” Edar signaling is crucial for controlling hair growth and regression.
55 citations
,
September 2014 in “Development” Wnt, Eda, and Shh pathways are crucial for different stages of sweat gland development in mice.
65 citations
,
June 2003 in “EMBO journal” Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.
6 citations
,
July 2023 in “Nature cell biology” SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.
1 citations
,
January 2011 in “ScholarlyCommons (University of Pennsylvania)” Notch signaling is crucial for specifying niche cells in Drosophila testis.
1 citations
,
April 2025 in “Pediatria i Medycyna Rodzinna” Restoring EDA and WNT pathways early may help improve skin, hair, and teeth issues in hypohidrotic ectodermal dysplasia.
176 citations
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September 2006 in “Stem Cells” BMP signaling prevents hair growth by stopping stem cell activation.
23 citations
,
October 2021 in “FEBS Journal” Sonic Hedgehog helps keep skin and airway barriers healthy and reduces inflammation.
December 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Hedgehog signaling controls hair follicle development and can affect skin cancer growth.
September 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Special gut cells help stem cells move to and fix injured areas by activating a specific signaling pathway.